Nephron

Treating shortness of breath, chest tightness, and wheezing associated with asthma, emphysema, and other breathing problems.

Nephron is a bronchodilator. It works by relaxing muscles in the airways to improve breathing.

Nephron is used to relieve occasional symptoms of asthma, such as wheezing, chest tightness, and feeling short of breath.

Nephron may also be used for purposes not listed in this medication guide.

Usual Adult Dose for Asthma - Acute

For temporary relief of shortness of breath, tightness of chest, and wheezing due to bronchial asthma.

Add 0.5 ml (contents of one vial) of solution to a hand-held rubber bulb nebulizer.

1 to 3 inhalations not more than every 3 hours.

Usual Pediatric Dose for Asthma - Acute

For temporary relief of shortness of breath, tightness of chest, and wheezing due to bronchial asthma in children 4 years old and older:

Add 0.5 ml (contents of one vial) of solution to a hand-held rubber bulb nebulizer: 1 to 3 inhalations not more than every 3 hours.

The use of this product by children should be supervised by an adult.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

See also:
What is the most important information I should know about Nephron?

Nephron is contraindicated in patients with known hypersensitivity to sympathomimetic amines, in patients with angle closure glaucoma, and patients in shock (nonanaphylactic). It should not be used in patients anesthetized with agents such as cyclopropane or halothane as these may sensitize the heart to arrhythmic action of sympathomimetic drugs.

Nephron should not ordinarily be used in those cases where vasopressor drugs may be contraindicated, e.g., in thyrotoxicosis, diabetes, in obstetrics when maternal blood pressure is in excess of 130/80 and in hypertension and other cardiovascular disorders.

Use exactly as directed on the label, or as prescribed by your doctor. Do not take more than the recommended dose. Using too much Nephron or using it too often can increase your risk of heart attack or stroke, which can cause death.

Nephron is a liquid solution that must be placed into a hand-held bulb nebulizer. You will inhale the medicine from the nebulizer.

Any child using Nephron should be supervised by an adult while using this medicine.

After using Nephron, your symptoms should improve within 20 minutes.

Call your doctor right away if your symptoms do not improve within 20 minutes, or if they get worse after using Nephron.

Asthma is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.

Seek medical attention if you think your medications are not working as well.

Signs that your asthma symptoms may be getting worse include:

• having to use more than 12 inhalations of Nephron in a 24-hour period;

• having to use more than 9 inhalations in 24 hours for 3 or more days in 1 week; or

• having more than 2 asthma attacks in 1 week.

Store at room temperature away from moisture, heat, and light. Do not freeze.

Do not use Nephron if it looks brown or cloudy. Throw it out and get a new supply of Nephron.

See also:
What other drugs will affect Nephron?

Nephron should be used cautiously in patients with hyperthyroidism, hypertension and cardiac arrhythmias. All vasopressors should be used cautiously in patients taking monoamine oxidase (MAO) inhibitors.

Nephron should not be administered concomitantly with other sympathomimetic drugs (such as isoproterenol) because of possible additive effects and increased toxicity.

Combined effects may induce serious cardiac arrhythmias. They may be administered alternately when the preceding effect of other such drug has subsided.

Administration of Nephron to patients receiving cyclopropane or halogenated hydrocarbon general anesthetics such as halothane which sensitize the myocardium, may induce cardiac arrhythmia.. When encountered, such arrhythmias may respond to administration of a beta-adrenergic blocking drug. Nephron also should be used cautiously with other drugs (e.g., digitalis, glycosides) that sensitize the myocardium to the actions of sympathomimetic drugs.

Diuretic agents may decrease vascular response to pressor drugs such as Nephron.

Nephron may antagonize the neuron blockade produced by guanethidine resulting in decreased antihypertensive effect and requiring increased dosage of the latter.

See also:
What are the possible side effects of Nephron?

Applies to Nephron: inhalation solution

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Headache; loss of appetite; nausea; nervousness; tremors; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur while taking Nephron (the active ingredient contained in Nephron)

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fast heartbeat; wheezing.

The active sympathomimetic hormone from the adrenal medulla in most species. It stimulates both the alpha- and beta- adrenergic systems, causes systemic vasoconstriction and gastrointestinal relaxation, stimulates the heart, and dilates bronchi and cerebral vessels. It is used in asthma and cardiac failure and to delay absorption of local anesthetics.