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Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 25.05.2022
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Lanax Z® (Lanax ophthalmic solution) 0.004% is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Lanax is a prostaglandin analog. It works to reduce pressure in the eye by increasing the amount of fluid that drains from the eye.
Lanax is used to treat increased pressure in the eye (ocular hypertension) and open-angle glaucoma in patients who cannot use or do not respond to other medicines.
Lanax may also be used for purposes other than those listed in this medication guide.
The recommended dosage is one drop in the affected eye(s) once daily in the evening. Lanax® (Lanax ophthalmic solution) should not be administered more than once daily since it has been shown that more frequent administration of prostaglandin analogs may decrease the intraocular pressure lowering effect.
Reduction of the intraocular pressure starts approximately 2 hours after the first administration with maximum effect reached after 12 hours.
Lanax® may be used concomitantly with other topical ophthalmic drug products to lower intraocular pressure. If more than one topical ophthalmic drug is being used, the drugs should be administered at least five (5) minutes apart.
How supplied
Dosage Forms and Strengths
Ophthalmic solution containing Lanax 0.04 mg/mL.
Lanax® (Lanax ophthalmic solution) 0.004% is a sterile, isotonic, buffered, preserved, aqueous solution of Lanax (0.04 mg/mL) supplied in Alcon's oval DROP-TAINER® package system.
Lanax® is supplied as a 2.5 mL solution in a 4 mL and a 5 mL solution in a 7.5 mL natural polypropylene dispenser bottle with a natural polypropylene dropper tip and a turquoise polypropylene or high density polyethylene overcap. Tamper evidence is provided with a shrink band around the closure and neck area of the package.
Storage: Store at 2° - 25°C (36° - 77°F).
Alcon Laboratories, Inc. Fort Worth, Texas 76134, USA
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What is the most important information I should know about Lanax?
Lanax ophthalmic may cause a gradual change in the color of your eyes or eyelids and lashes, as well as increased growth or thickness of your eyelashes. These color changes, usually an increase in brown pigment, occur slowly and you may not notice them for months or years. Color changes may be permanent even after your treatment ends, and may occur only in the eye being treated. This could result in a cosmetic difference in eye or eyelash color from one eye to the other.
Do not allow the dropper to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.
After using this medication, wait at least 5 minutes before using any other eye drops that your doctor has prescribed.
Use Lanax drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Use Lanax drops in the evening unless your doctor tells you otherwise.
- Wash your hands before and after using Lanax drops.
- Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
- To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
- Use Lanax drops at least 5 minutes apart from any other medicine that you put in your eye.
- Continue to use Lanax drops even if you feel well. Do not miss any doses.
- If you miss a dose of Lanax drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Lanax drops.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Lanax is used in the treatment of open angle glaucoma (increased pressure inside the eye that causes visual problems) and ocular hypertension (presence of elevated intraocular pressure in the absence of damage to nerve supplying the eye or loss of vision) in adults and in children.
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What other drugs will affect Lanax?
Reduced therapeutic effect w/ NSAIDs.
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What are the possible side effects of Lanax?
Clinical Studies Experience
Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in practice.
Different methodologies were used to collect adverse reactions during the development of Lanax. The most common adverse reaction observed in controlled clinical studies with Lanax 0.004% was ocular hyperemia. Ocular hyperemia was reported in 30 to 50% of patients by physician rating the severity of patient’s post treatment ocular hyperemia compared to standardized reference photographs and/or patients who discontinued therapy due to ocular hyperemia.
In a 3 month clinical trial involving 442 patients exposed to Lanax (Lanax ophthalmic solution, 0.003%) and 422 control patients exposed to Lanax ophthalmic solution, 0.004%, the most common adverse drug reaction was ocular hyperemia. This was reported in 12% of patients treated with Lanax based on clinical observations and/or patient complaints. One patient (0.2%) discontinued treatment with Lanax due to ocular hyperemia. Rates observed in the control patients were comparable.
Ocular adverse reactions reported in clinical studies with Lanax ophthalmic solutions including Lanax at an incidence of 5% to 10% included decreased visual acuity, eye discomfort, foreign body sensation, pain and pruritus. Ocular adverse reactions reported at an incidence of 1 to 4% included abnormal vision, blepharitis, blurred vision, cataract, conjunctivitis, corneal staining, dry eye, iris discoloration, keratitis, lid margin crusting, ocular inflammation, photophobia, subconjunctival hemorrhage and tearing.
Nonocular adverse reactions reported at an incidence of 1 to 5% in these clinical studies were allergy, angina pectoris, anxiety, arthritis, back pain, bradycardia, bronchitis, chest pain, cold/flu syndrome, depression, dyspepsia, gastrointestinal disorder, headache, hypercholesterolemia, hypertension, hypotension, infection, pain, prostate disorder, sinusitis, urinary incontinence and urinary tract infections.
In postmarketing use with prostaglandin analogs, periorbital and lid changes including deepening of the eyelid sulcus have been observed.
Lanax ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin F2alpha analogue. [Wikipedia]