Hemostam

Copper (Hemostam) has been designed for the demands of modern life. With a wide range of nutrients and trace minerals, Copper (Hemostam) gives nutritional support to the area of health which are most relevance to women.

Each cap contains starflower oil 100 mg, evening primrose oil 100 mg, citrus bioflavonoids 10 mg, natural mixed carotenoids 2 mg, vitamin D (as D3 200 IU) 5 mcg, vitamin E 30 mg, vitamin C 60 mg, vitamin K 90 mcg, thiamin (vitamin B1) 10 mg, riboflavin (vitamin B2) 5 mg, niacin (vitamin B3) 36 mg, vitamin B6 10 mg, folic acid 400 mcg, vitamin B12 20 mcg, biotin 50 mcg, pantothenic acid 6 mg, magnesium 100 mg, iron 12 mg, zinc 12 mg, Copper (Hemostam) 1500 mcg, manganese 2.5 mg, selenium 100 mcg, chromium 50 mcg, para-aminobenzoic acid (PABA) 30 mg.

No artificial colours, gluten, presevatives, starch or sugar, salt or yeast.

Copper (Hemostam) has not been tested on animals.

Each 5 mL syrup contains: Diastase (1:50) 135 mg, pepsin 50 mg, papain BPC 50 mg, vitamin B₁ 5 mg, vitamin B₂ 2 mg, vitamin B₆ 2 mg, vitamin B₁₂ 5 mcg, calcium pantothenate 1 mg and nicotinamide 20 mg.

Iron (Hemostam) is a pleasantly flavoured syrup, containing digestive enzymes and vitamins of the B-complex group. Abdominal cramps, flatulence, heartburn and nausea can occur as a result of indigestion. Iron (Hemostam) is the ideal cure to facilitate digestion and to strengthen the GIT.

Iron (Hemostam)'s balanced formulation provides an ideal supplementation that meets the demands and replenishes vitamins stores in the body.

3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride.

Vitamin B12 (Hemostam) (commonly known as Vitamin B12 (Hemostam)) is the most chemically complex of all the vitamins. Vitamin B12 (Hemostam)'s structure is based on a corrin ring, which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded. The central metal ion is Co (cobalt). Vitamin B12 (Hemostam) cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of cyanocobalamin are bacteria and archaea. Higher plants do not concentrate cyanocobalamin from the soil and so are a poor source of the substance as compared with animal tissues. Vitamin B12 (Hemostam) is naturally found in foods including meat (especially liver and shellfish), eggs, and milk products.

Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide.

Vitamin B3 (Hemostam) Lotion: Helps to reduce the appearance of blemishes on larger areas (back and upper chest). It absorbs easily to the skin and does not bleach clothes. Non-photosensitizing, fragrance-free and paraben-free.

Vitamin B3 (Hemostam) Isocorrexion Hydrating Cream: Specially formulated for acne prone skin. Nicotinamide and Anti-Bacterial Adhesive substance (ABA's) helps to clear blemishes. Biophytosebum provides a moisturizing effect, reducing dryness and skin tightness caused by conventional acne treatment.

Vitamin B3 (Hemostam) Oil-Free Cream: An oil-free formula enriched with mattifying agents. It helps to clear blemishes by promoting oil-free skin.

Vitamin B3 (Hemostam) UV High Protection Cream SPF 45: Protects acne-prone skin from daily sun-induced irritation and damage, keeping the skin hydrated and blemish-free at the same time. Non-sensitizing, non-comodogenic, fragrance-free and paraben-free.

Vitamin B3 (Hemostam) Gel: Provides intensive anti-blemish skin care for localized spots and promotes disappearance on the face or other small areas. It is non-sensitizing, fragrance-free and paraben-free.

Vitamin B3 (Hemostam) Moussant Soap Free Cleansing Gel: Helps clear blemishes by purifying and cleansing the skin gently.

The 4-methanol form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990).

Copper (Hemostam) 0.4 mg/mL (Cupric Chloride Injection, USP) is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN). Administration helps to maintain Copper (Hemostam) serum levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.

Film-Coated Tablet: Treatment of Iron (Hemostam) deficiency. Prevention of Iron (Hemostam) deficiency during pregnancy.

Syrup: All cases of Iron (Hemostam) deficiency and Iron (Hemostam) deficiency anaemia.

Drops: General: Hypochromic or masked Iron (Hemostam) deficiency anaemias. General weakness. Convalescence. Blood losses. Tropical microcytic anaemia. Anaemias due to infections. For maintenance therapy in pernicious anaemia. As an adjuvant in treating chronically ill or undernourished patients.

Women: Iron (Hemostam) deficiency due to menstruation. During and after pregnancy and lactation. Menorrhagia.

Children: All types of hypochromic anaemias and masked Iron (Hemostam) deficiencies. Inappetence. Retarded growth. Weakness. Unsound dietary habits. To speed up restoration of depleted Iron (Hemostam) reserves.

Vitamin B1 (Hemostam) deficiency

Pernicious anemia, both uncomplicated and accompanied by nervous system involvement.

Dietary deficiency of Vitamin B12 (Hemostam), occurring in strict vegetarians and in their breast-fed infants. (Isolated Vitamin B12 (Hemostam) deficiency is very rare).

Malabsorption of Vitamin B12 (Hemostam), resulting from structural or functional damage to the stomach, where intrinsic factor is secreted or to the ileum, where intrinsic factor facilitates Vitamin B12 (Hemostam) absorption. These conditions include tropical sprue, and nontropical sprue (idiopathic steatorrhea, gluten-induced enteropathy). Folate deficiency in these patients is usually more severe than Vitamin B12 (Hemostam) deficiency.

Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy). Total gastrectomy always produces Vitamin B12 (Hemostam) deficiency.

Structural lesions leading to Vitamin B12 (Hemostam) deficiency include regional ileitis, ileal resections, malignancies, etc.

Competition for Vitamin B12 (Hemostam) by intestinal parasites or bacteria.

The fish tapeworm (Diphyilobothrium latum) absorbs huge quantities of Vitamin B12 (Hemostam) and infested patients often have associated gastric atrophy. The blind-loop syndrome may produce deficiency of Vitamin B12 (Hemostam) or folate.

Inadequate utilization of Vitamin B12 (Hemostam). This may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia.

For the Schilling Test.

Vitamin B2 (Hemostam) deficiency

Helps clear blemishes. Vitamin B3 (Hemostam) Moussant Soap-Free Cleansing Gel Purifies & cleanses the skin. Vitamin B3 (Hemostam) Oil-Free Cream Promotes oil-free skin. Vitamin B3 (Hemostam) Isocorrexion Use for acne prone skin. Reduces skin dryness & tightness caused by conventional acne treatment. Vitamin B3 (Hemostam) Lotion For body acne in chest & back. Vitamin B3 (Hemostam) UV High Protection Cream SPF 45 For sun protection for acne prone skin. Vitamin B3 (Hemostam) Gel For localized spots.

Coenzyme A (metabolite of dexpanthenol) is important for deep penetrating moisturizer; stimulates epithelization; has wound healing effect; has an anti-inflammatory effect.

Only the D-Panthenol is the provitamin of D-Pantothenic acid (Vitamin B5 (Hemostam)), not the L-Panthenol.

A cream with dexpanthenol regularly applied to the skin improves the moisture content of dry skin significantly.

A cream with 5% dexpanthenol accelerates the healing of superficial wounds by approximately 30%.

An ointment with dexpanthenol prevents erythema due to UV light.

Dexpanthenol ointment also protects the lips against solar herpes, Sun burns, mild burns, skin irritations, dry or cracked skin, cosmetic or shaving rashes, post chemical peeling treatment, post laser resurfacing treatment ( 11th -15th day).

Dexpanthenol is effective for preventing / treating nappy dermatitis in infants.

* Sideroblastic anaemia

* Treatment and prophylaxis of Vitamin B6 (Hemostam) deficiency states

Supplementing Iron (Hemostam) in the diet and treating or preventing low levels of Iron (Hemostam) in the blood. It may also be used for other conditions as determined by your doctor.

Iron (Hemostam) suspension is a mineral. It works by providing Iron (Hemostam) to the body.

Thiamine is Vitamin B1 (Hemostam). Thiamine is found in foods such as cereals, whole grains, meat, nuts, beans, and peas. Thiamine is important in the breakdown of carbohydrates from foods into products needed by the body.

Thiamine is used to treat or prevent Vitamin B1 (Hemostam) deficiency. Thiamine injection is used to treat beriberi, a serious condition caused by prolonged lack of Vitamin B1 (Hemostam).

Thiamine taken by mouth (oral) is available without a prescription. Injectable thiamine must be given by a healthcare professional.

Thiamine may also be used for purposes not listed in this medication guide.

Cyanocobalamin is a man-made form of Vitamin B12 (Hemostam). Vitamin B12 (Hemostam) is important for growth, cell reproduction, blood formation, and protein and tissue synthesis.

Cyanocobalamin is used to treat Vitamin B12 (Hemostam) deficiency in people with pernicious anemia and other conditions.

Cyanocobalamin may also be used for purposes not listed in this medication guide.

Riboflavin is Vitamin B2 (Hemostam). Vitamins are naturally occurring substances necessary for many processes in the body. Riboflavin is important in the maintenance of many tissues of the body.

Riboflavin is used to prevent and to treat deficiencies of riboflavin.

Riboflavin may also be used for other purposes not listed in this medication guide.

Pyridoxine is Vitamin B6 (Hemostam). Vitamins occur naturally in foods such as meat, poultry, nuts, whole grains, bananas, and avocados. Vitamin B6 (Hemostam) is important for many processes in the body.

Pyridoxine is used to treat or prevent Vitamin B6 (Hemostam) deficiency. It is also used to treat a certain type of anemia (lack of red blood cells). Pyridoxine injection is also used to treat some types of seizure in babies.

Pyridoxine taken by mouth (oral) is available without a prescription. Injectable pyridoxine must be given by a healthcare professional.

Pyridoxine may also be used for purposes not listed in this medication guide.

Copper (Hemostam) 0.4 mg/mL (Cupric Chloride Injection, USP) contains 0.4 mg Copper (Hemostam)/mL and is administered intravenously only after dilution. The additive should be diluted in a volume of fluid not less than 100 mL. For the adult receiving TPN, the suggested additive dosage is 0.5 to 1.5 mg Copper (Hemostam)/day (1.25 to 3.75 mL/day). For pediatric patients, the suggested additive dosage is 20 mcg Copper (Hemostam)/kg/day (0.05 mL/kg/day). Infants weighing less than 1500 gm may have increased requirements because of their low body reserves and increased requirements for growth.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

Film-Coated Tablet: Treatment of Iron (Hemostam) Deficiency with Reduced Number of Red Blood Cells in Adults and Children over 12 Years: 1 to 3 tablets once daily or divided into separate doses for about 3 to 5 months.

After normalisation of the red blood pigment (haemoglobin) value, continue with 1 tablet once daily for several weeks. This will replenish the Iron (Hemostam) stores.

Treatment of Iron (Hemostam) Deficiency with Reduced Number of Red Blood Cells in Pregnancy: 2 to 3 tablets once daily or divided into separate doses.

After normalisation of the red blood pigment value, continue with 1 tablet once daily until, at least, the end of pregnancy. This will replenish the Iron (Hemostam) stores and provide the increased amount of Iron (Hemostam) required during pregnancy.

Treatment of Iron (Hemostam) Deficiency with Normal Number of Red Blood Cells in Adults, Pregnancy, and Children over 12 years, and Prevention of Iron (Hemostam) Deficiency in Pregnancy: 1 tablet once daily for 1 to 2 months.

Syrup:

Children: 5 mL 1 to 2 times daily before meals.

Infants: Begin with 2.5 mL daily and gradually increase to 5 mL daily.

Drops: Adults: 20 drops 2 to 3 times daily during or after a meal.

Children: 20 drops 1 to 2 times daily during or after a meal.

Infants: Begin with 6 drops daily and gradually increase to 20 drops daily.

Iron (Hemostam) may be mixed with fruit, vegetable juices or other liquids if desired.

Best results are obtained by adequate dosage and regular administration. It is recommended that the therapy in conformity to the degree of Iron (Hemostam) deficiency should be continued for at least 1 to 2 months.

Administration: Take Iron (Hemostam) during or immediately after meal.

Duration of use depends upon the degree of Iron (Hemostam) deficiency.

Do not discontinue sooner than recommended as this may reduce the success of therapy.

Vitamin B12 (Hemostam) Atlantic Laboratories is used as injections SC, IV, IM, intralumbar, and also oral. With anemia associated with Vitamin B12 (Hemostam) deficiency is introduced on 100-200 mcg in 2 days. In anemia with symptoms of funicular myelosis and megalocytic anemia with diseases of the nervous system - 400-500 micrograms in the first 7 days daily, then 1 time every 5-7 days. In the period of remission in the absence of events funicular myelosis maintenance dose - 100 mcg 2 times a month, in the presence of neurological symptoms - at 200-400 mcg 2-4 times a month. In acute post-hemorrhagic anemia and iron anemia by 30-100 mcg 2-3 times a week. When aplastic anemia (especially in children) - 100 micrograms before clinical improvement. When nutritional anemia in infants and preterm - 30 mcg / day during 15 days.

In diseases of the central and peripheral nervous system and neurological diseases with a pain syndrome is administered in increasing doses - 200-500 mcg, with the improvement in the state - 100 mcg / day. The course of treatment with Vitamin B12 (Hemostam) Atlantic Laboratories is 2 weeks. In traumatic lesions of peripheral nervous system - at 200-400 mcg every other day for 40-45 days.

When hepatitis and cirrhosis - 30-60 mcg / day or 100 mg every other day for 25-40 days.

Dystrophy in young children, Down syndrome and cerebral palsy - by 15-30 mcg every other day.

When funicular myelosis, amyotrophic lateral sclerosis can be introduced into the spinal canal at 15-30 mcg, gradually increasing the dose of 200-250 micrograms.

In radiation sickness, diabetic neuropathy, sprue - by 60-100 mcg daily for 20-30 days.

When deficiency of Vitamin B12 (Hemostam) to prevent - IV or IM for 1 mg 1 time a month; for treatment - IV or IM for 1 mg daily for 1-2 weeks, the maintenance dose is 1-2 mg IV or IM from 1 per week, up to 1 per month. Duration of treatment is determined individually.

Vitamin B3 (Hemostam) Lotion: Apply to the areas being treated after cleansing twice a day, AM & PM.

Vitamin B3 (Hemostam) Isocorrexion & Vitamin B3 (Hemostam) Oil-Free Cream: Apply to the face and affected areas (neck, chest and back) after cleansing twice a day, AM & PM. Massage delicately to facilitate absorption.

Vitamin B3 (Hemostam) UV High Protection Cream SPF 45: Reapply every 2-3 hrs.

Vitamin B3 (Hemostam) Gel: Apply small amount of gel on affected areas by massaging gently in AM & PM.

Vitamin B3 (Hemostam) Moussant Soap Free Cleansing Gel: Apply in AM & PM to damp skin, face and affected areas (neck, chest and back) by massaging delicately. Rinse thoroughly and dry gently. May be used in shower.

Pregnancy or suspected malignant genital tumor of its existence, acute inflammation, subacute or chronic genital tract, congenital or acquired anatomic abnormalities of the uterus and cervix, endometriosis, malposition and malsituaciones accused the uterus, uterine hypoplasia, genital bleeding of unknown etiology blood clotting disorders, Wilson’s disease, allergy to Copper (Hemostam).

See also:
What is the most important information I should know about Iron (Hemostam)?

All cases of Iron (Hemostam) overload and disturbances in utilization of Iron (Hemostam).

Film-Coated Tablet: Allergy to Iron (Hemostam) (III)-hydroxide polymaltose complex or any of the other ingredients of Iron (Hemostam).

An Iron (Hemostam) overload in the body.

Disturbed use of Iron (Hemostam) by the body.

Reduced number of red blood cells (anaemia), not caused by Iron (Hemostam) deficiency, such as due to increased red blood cell breakdown, vitamin B₁₂ deficiency.

See also:
What is the most important information I should know about Vitamin B1 (Hemostam)?

Contraindications for Vitamin B1 (Hemostam) (Vitamin B1 (Hemostam))

Hypersensitivity to Vitamin B1 (Hemostam) or any component of a product containing Vitamin B1 (Hemostam).

See also:
What is the most important information I should know about Vitamin B12 (Hemostam)?

Hypersensitivity to the components of the formula. History of allergy to the cobalamins (Vitamin B12 (Hemostam) and similar substances). Malignant tumors. By stimulating the growth of tissues, the Cobamamide could increase the high rate of cell multiplication. Sensitivity to cobalt. History of allergies to cobalamin (Vitamin B12 (Hemostam) and related substances).

- Malignant tumor: Due to the action of Vitamin B12 (Hemostam) on the growth of tissue cell multiplication rate high, the risk of exacerbation should be taken into account.

- Children under 6 years because of the dosage form

See also:
What is the most important information I should know about Vitamin B2 (Hemostam)?

None well documented.

Contraindications for Vitamin B3 (Hemostam) (Vitamin B3 (Hemostam))

Nicotinic acid is contraindicated in patients with a known hypersensitivity to any component of this medication; significant or unexplained hepatic dysfunction; active peptic ulcer disease; or arterial bleeding.

Haemophiliacs, patients with ileus (due to mechanical obstruction).

See also:
What is the most important information I should know about Vitamin B6 (Hemostam)?

Contraindications for Vitamin B6 (Hemostam) (Vitamin B6 (Hemostam))

Vitamin B6 (Hemostam) is contraindicated in those hypersensitive to any component of a Vitamin B6 (Hemostam)-containing product.

Use Iron (Hemostam) suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Iron (Hemostam) suspension is absorbed better on an empty stomach but may be taken with food if it upsets your stomach. Some foods (eg, eggs, whole grain breads, cereal, dairy products, coffee, tea) may decrease the amount of Iron (Hemostam) absorbed by your body. Talk with your doctor about the best way to take Iron (Hemostam) suspension with food if it upsets your stomach.
• Shake well before using.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• Take Iron (Hemostam) suspension with a full glass (8 oz [240 mL]) of water.
• Do not lie down for 30 minutes after taking Iron (Hemostam) suspension.
• If you take an antacid, a bisphosphonate (eg, alendronate), cefdinir, eltrombopag, methyldopa, penicillamine, a quinolone antibiotic (eg, ciprofloxacin), or a tetracycline (eg, minocycline), ask your doctor or pharmacist how to take it with Iron (Hemostam) suspension.
• If you miss a dose of Iron (Hemostam) suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Iron (Hemostam) suspension.

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Pyridoxine tablets are taken by mouth. Injectable pyridoxine is injected into a muscle or into a vein through an IV. You may be shown how to use injections at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

The recommended dietary allowance of pyridoxine increases with age. Follow your healthcare provider's instructions. You may also consult the Office of Dietary Supplements of the National Institutes of Health, or the U.S. Department of Agriculture (USDA) Nutrient Database (formerly "Recommended Daily Allowances") listings for more information.

Pyridoxine is only part of a complete program of treatment that may also include a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you should eat or avoid to help control your condition.

Store at room temperature away from moisture and heat.

Use: Labeled Indications

Trace element added to parenteral nutrition (PN) to prevent Copper (Hemostam) deficiency; orally as a dietary supplement

Vitamin B2 (Hemostam) (riboflavin) supplementation is used to prevent and treat riboflavin deficiency. Vitamin B2 (Hemostam) may prevent migraine headaches at high doses and be useful for prevention of eye conditions such as cataract, glaucoma and tired eyes (fatigue). Vitamin B2 (Hemostam) is also used for boosting of immune system, and maintenance of healthy hair, skin, nails and mucous membranes.

Hypercholesterolaemia, hyperlipidemia, hypertriglyceridaemia, pellagra.

It is used for the treatment and prevention of Vitamin B6 (Hemostam) deficiency. It is important for the breakdown of protein, fats, and carbohydrates from foods.

Ascorbic Acid: Copper (Hemostam) may decrease the serum concentration of Ascorbic Acid. Management: To minimize the risk for ascorbic acid degradation, add multivitamin product to TPN solution immediately prior to infusion or administer multivitamin and Copper (Hemostam) in separate containers. Consider therapy modification

Drug interactions were not noted and were not studied in clinical studies.

Feridex I.V. (ferumoxides injectable solution) administration provides elemental Iron (Hemostam). In patients who are receiving supplemental Iron (Hemostam) orally or parenterally, the dose of supplemental Iron (Hemostam) may need to be decreased.

The effect of concomitant parenteral Iron (Hemostam) on Feridex I.V. dosing is not known.

Laboratory Test Findings

Serum Iron (Hemostam) levels may be above the normal range following Feridex I.V. (ferumoxides injectable solution) administration. Transient increases in serum Iron (Hemostam) of 15–100% of baseline were observed 18 to 24 hours after Feridex I.V. (ferumoxides injectable solution) administration, and returned to normal in most patients by 7 days after administration. Increases in serum ferritin levels were seen 1 to 7 days after administration.

In a Phase 1 study in normal subjects, PTT was statistically significantly increased; however, all values were within the normal range and no subjects had a more than 40% increase from baseline. In clinical trials of patients who had baseline hematologic abnormalities associated with underlying liver disease, an effect of Feridex I.V. (ferumoxides injectable solution) on platelet or PTT was not demonstrated. In patients with low hematocrit and hemoglobin, over a period of 48 hours to 7 days after Feridex I.V. (ferumoxides injectable solution), the serum Iron (Hemostam), the hematocrit and hemoglobin levels increase slightly.

See also:
What other drugs will affect Vitamin B1 (Hemostam)?

Interactions for Vitamin B1 (Hemostam) (Vitamin B1 (Hemostam))

Loop Diuretics,

Oral Contraceptives, Stavudine, Tricyclic Antidepressants

See also:
What other drugs will affect Vitamin B12 (Hemostam)?

In an application of Vitamin B12 (Hemostam) Atlantic Laboratories with hormonal contraceptives for oral administration may decrease the concentration of cyanocobalamin in plasma.

In an application with anticonvulsant drugs decreased cyanocobalamin absorption from the gut.

In an Vitamin B12 (Hemostam) Atlantic Laboratories application with neomycin, aminosalicylic acid, colchicine, cimetidine, ranitidine, drugs potassium decreased cyanocobalamin absorption from the gut.

Cyanocobalamin may exacerbate allergic reactions caused by thiamine.

When parenteral application of chloramphenicol may decrease the hematopoietic effects of cyanocobalamin with anemia.

See also:
What other drugs will affect Vitamin B2 (Hemostam)?

Interactions for Vitamin B2 (Hemostam) (Vitamin B2 (Hemostam))

Alcohol - impairs the intestinal absorption of riboflavi

Antidepressants (tricyclics or phenothiazines) - requirements for riboflavin may be increased in patients receiving these medications

Probenecid - concurrent use decreases gastrointestinal absorption of riboflavin; requirements for riboflavin may be increased in patients receiving probenecid.

Interactions for Vitamin B3 (Hemostam) (Vitamin B3 (Hemostam))

Antihypertensive Therapy: Nicotinic acid may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension

Aspirin: Concomitant aspirin may decrease the metabolic clearance of nicotinic acid. The clinical relevance of this finding is unclear

Other: Concomitant alcohol or hot drinks may increase the side effects of flushing and pruritus and should be avoided at the time of drug ingestion.

Dextropanthenyl alcohol in combination with hydrocortisone may be more effective than topical hydrocortisone alone in some dermatoses.

See also:
What other drugs will affect Vitamin B6 (Hemostam)?

Interactions for Vitamin B6 (Hemostam) (Vitamin B6 (Hemostam))

Amiodarone: Concomitant use of Vitamin B6 (Hemostam) and amiodarone may enhance amiodarone-induced photosensitivity reactions. Doses of Vitamin B6 (Hemostam) greater than 5-10 milligrams/day should be avoided by those taking amiodarone Carbamazepine: Chronic use of carbamazepine may result in a significant decrease in plasma pyridoxal 5-phosphate levels Cycloserine: Cycloserine may react with pyridoxal 5-phosphate to form a metabolically inactive oxime, which may result in a functional Vitamin B6 (Hemostam) deficiency Ethionamide: The use of ethionamide may increase Vitamin B6 (Hemostam) requirements Fosphenytoin: High doses of Vitamin B6 (Hemostam) may lower plasma levels of phenytoin. Fosphenytoin is a prodrug of phenytoin Hydralazine: The use of hydralazine may increase Vitamin B6 (Hemostam) requirements Isoniazid: (isonicotinic acid, INH). Isoniazid reacts with pyridoxal 5-phosphate to form a metabolically inactive hydrazone, which may result in functional Vitamin B6 (Hemostam) deficiency Levodopa: Concomitant use of levodopa and Vitamin B6 (Hemostam) in doses of 5 milligrams or more daily may reverse the therapeutic effects of levodopa. Vitamin B6 (Hemostam) does not reverse the therapeutic effects of levodopa if levodopa is taken concurrently with the levodopa decarboxylase inhibitor carbidopa. Levodopa is typically administered as a combination product with carbidopa

Oral contraceptives: The use of oral contraceptives may increase Vitamin B6 (Hemostam) requirements. This was more the case with the older oral contraceptive agents with high-dose estrogen/progestin. It appears to be less the case with the newer low-dose estrogen/progestin products Penicillamine: Penicillamine may react with pyridoxal 5-phosphate to form a metabolically inactive thiazolidine, which may result in a functional Vitamin B6 (Hemostam) deficiency Phenelzine: Phenelzine may react with pyridoxal 5-phosphate to yield a metabolically inactive hydrazone compound Phenobarbital: High doses of Vitamin B6 (Hemostam) may lower plasma levels of phenobarbital Phenytoin: High doses of Vitamin B6 (Hemostam) may lower plasma levels of phenytoin Theophylline: Theophylline may react with pyridoxal 5-phosphate leading to low plasma levels of the coenzyme. This may increase the risk of theophylline-induced seizures Valproic acid: Chronic use of valproic acid may result in a significant decrease in plasma pyridoxal 5-phosphate levels.

Adverse Reactions

Generally well tolerated; excessive Copper (Hemostam) levels may result in the following adverse effect.

Hepatic: Hepatic insufficiency (including hepatic necrosis)

See also:
What are the possible side effects of Iron (Hemostam)?

Applies to carbonyl Iron (Hemostam): suspension

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; darkened or green stools; diarrhea; loss of appetite; nausea; stomach cramps, pain, or upset; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur while taking carbonyl Iron (Hemostam):

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or tarry stools; blood or streaks of blood in the stool; fever; severe or persistent nausea, stomach pain, or vomiting; vomit that looks like blood or coffee grounds.

See also:
What are the possible side effects of Vitamin B1 (Hemostam)?

Applies to thiamine: capsule, solution, tablet, tablet enteric coated

As well as its needed effects, thiamine (the active ingredient contained in Vitamin B1 (Hemostam)) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking thiamine, check with your doctor immediately:

Rare - Soon after receiving injection only

• Coughing
• difficulty in swallowing
• hives
• itching of skin
• swelling of face, lips, or eyelids
• wheezing or difficulty in breathing

See also:
What are the possible side effects of Vitamin B12 (Hemostam)?

Applies to cyanocobalamin: intramuscular solution

Other dosage forms:

• nasal gel/jelly, nasal spray

As well as its needed effects, cyanocobalamin (the active ingredient contained in Vitamin B12 (Hemostam)) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking cyanocobalamin, check with your doctor or nurse immediately:

Incidence not known:

• Abdominal or stomach pain
• bleeding from the gums or nose
• blue lips and fingernails
• chest pain
• cough
• coughing that sometimes produces a pink frothy sputum
• decreased urine output
• difficult, fast, noisy breathing, sometimes with wheezing
• difficulty with swallowing
• dilated neck veins
• dizziness
• extreme fatigue
• eye pain
• fast heartbeat
• headache
• hives, itching, or skin rash
• increased sweating
• irregular breathing
• irregular heartbeat
• pale skin
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• ringing in the ears
• swelling of the face, fingers, feet, or lower legs
• tightness in the chest
• unusual tiredness or weakness
• weight gain

Minor Side Effects

Some cyanocobalamin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Incidence not known:

• Diarrhea
• skin rash with a general disease

See also:
What are the possible side effects of Vitamin B2 (Hemostam)?

Genitourinary

Yellow-orange discoloration of urine.

Allergic sensitization has been reported rarely following oral and parenteral administration of Folic Acid.

At recommended doses, nicotinamide is expected to be well tolerated. Gastrointestinal distress such as nausea or vomiting have been associated with the administration of nicotinamide or zinc at doses greater than the recommended dose of nicotinamide

Nicotinamide: Dizziness, headache, hyperglycemia, nausea, vomiting, diarrhea, elevations in liver function tests, hepatotoxicity, blurred vision, flushing, rash.

No serious side effects have been reported, even at intakes of up to 10,000 mg (10 grams) per day. Very large amounts of pantothenic acid (several grams per day) can cause diarrhea.

Pantothenic acid works together with Vitamin B5 (Hemostam), Vitamin B5 (Hemostam), and Vitamin B5 (Hemostam) to help make the fuel our bodies run on—ATP.

There is one report of a 76-year-old woman who developed a life-threatening condition (eosinophilic pleuropericardial effusion) while taking 300 mg of pantothenic acid per day and 10 mg of biotin per day.2 However, it is not clear whether the vitamins caused the problem.

See also:
What are the possible side effects of Vitamin B6 (Hemostam)?

Applies to pyridoxine: capsule, injectable, solution, tablet, tablet enteric coated, tablet extended release

As well as its needed effects, pyridoxine (the active ingredient contained in Vitamin B6 (Hemostam)) may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking pyridoxine, check with your doctor or nurse as soon as possible:

With large doses

• Clumsiness
• numbness of hands or feet