Complevit

Each film-coated tablet contains vitamins B1 (Thiamine (Complevit) disulfide) 100 mg, vitamin B6 (Pyridoxine (Complevit) hydrochloride) 200 mg and vitamin B12 (cyanocobalamin) 200 mcg.

It also contains the following excipients: Montan-glycol wax, gelatin, methylcellulose, acacia, magnesium stearate, glycerol 85%, povidone 25, calcium carbonate, colloidal silicon dioxide, corn starch, kaolin, lactose monohydrate, talc, sucrose and titanium dioxide.

Complevit is a combination of the 3 essential neurotropic vitamins (B1, B6 and B12) in high dosage. Vitamins B1, B6 and B12 are of special importance for the metabolism in the peripheral and central nervous system. Their effect on the regeneration of nerves has been shown in various investigations using the vitamins individually and in combination.

Vitamin B1 plays an important role in major metabolic processes. Vitamin B6 has an analgesic effect. Vitamin B12 ensures blood cell formation and prevents degenerative processes of the nervous system. Both the individual function and the beneficial biochemical links between the 3 vitamins justify their combined use.

Each 3-mL ampoule contains the following 3 essential neurotropic vitamins of the B group: Vitamin B1 (Thiamine (Complevit) hydrochloride) 100 mg, vitamin B6 (pyridoxol hydrochloride) 100 mg, vitamin B12 5000 mcg.

Film-Coated Tablet: Neurological and other disorders associated with disturbance of metabolic functions influenced by B-complex vitamins, including diabetic polyneuropathy, alcoholic peripheral neuritis and post-influenzal neuropathies.

Treatment of neuritis and neuralgia of the spinal nerves, especially facial paresis, cervical syndrome, low back pain, and ischialgia.

Injection: Treatment of disorders of the peripheral nervous system: Polyneuritis, neuralgia, sciatica and shoulder-arm syndrome, lumbago-lumbalgia, intercostals neuralgia, trigeminal neuralgia, facial palsy, herpes zoster, diabetic neuropathy, optic neuritis, numbness of the extremities; as a supplement to the therapy with isoniazid, reserpine and the phenothiazines; hyperemesis gravidarum, vitamin B deficiency, cerebrovascular accidents.

Supplement therapy with isoniazid, resperpine and phenothiazines.

Film-Coated Tablet: 1 tab 3 times daily to treat moderate cases, or to provide interval and follow-up therapy for a course of injections.

The duration of the treatment is determined by the physician.

Injection: Severe Cases: 1 amp daily by deep IM (intragluteal). Milder Cases/Follow-Up Therapy: 1 amp IM 2-3 times weekly.

Administration: Complevit tab are swallowed without chewing with a little liquid with or after meals.

Hypersensitivity to any of the active ingredients or excipients of Complevit.

Use in children: Complevit film-coated tablets are not suitable for the treatment of children due to the high content of vitamin B-complex.

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you take this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.

You should not take other medicines that contain paracetamol in combination with this medicine, as this can easily result in exceeding the maximum recommended daily dose of paracetamol. Many cold and flu remedies and over-the-counter painkillers contain paracetamol, so be sure to check the ingredients of any other medicines before taking them with this one. Migraleve yellow can be taken four hours after taking Migraleve pink if you still have a migraine, but make sure you do not exceed the maximum dose recommended in the information leaflet.

This medicine should be used with caution in people taking a monoamine oxidase inhibitor (MAOI), for example the antidepressants phenelzine, tranylcypromine or isocarboxacid. Ask your doctor or pharmacist for advice before taking this medicine if you have taken an MAOI in the last 14 days.

Cholestyramine reduces the absorption of paracetamol from the gut. It should not be taken within an hour of taking paracetamol or the effect of the paracetamol will be reduced.

Metoclopramide and domperidone may increase the absorption of paracetamol from the gut.

Long-term or regular use of paracetamol may increase the anti-blood-clotting effect of warfarin and other anticoagulant medicines, leading to an increased risk of bleeding. This effect does not occur with occasional painkilling doses. If you are taking an anticoagulant medicine and you are also taking co-codamol regularly, your blood clotting time (INR) should be regularly monitored.

In the unlikely event that this medicine makes you feel drowsy, this may be enhanced by other medicines that can cause drowsiness, such as the following:

antipsychotics, eg haloperidol

barbiturates, eg phenobarbital, amobarbital

benzodiazepines, eg diazepam, temazepam

other opioids, eg morphine, dihydrocodeine

sedating antihistamines, eg chlorphenamine, hydroxyzine

sleeping tablets, eg zopiclone

tricyclic antidepressants, eg amitriptyline.

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Constipation.

Skin rash.

Codeine can cause drowsiness, although at the dose contained in this medicine this is very unlikely. However, if you do find this medicine makes you feel sleepy or dizzy you should not drive or operate machinery and avoid alcoholic drink.

The side effects listed above may not include all of the side effects reported by the medicines’s manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.