Components:
Treatment option:
Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 04.04.2022
Attention! Information on this page is intended only for medical professionals! Information is collected in open sources and may contain significant errors! Be careful and double-check all the information on this page!
Ciprid (Cisapride)
Cisapride
Gastric and intestinal paresis, gastric dyspepsia, reflux esophagitis, chronic constipation, regurgitation in newborns.
Inside. The dose is set individually. Adult: according to 5-20 mg 2-4 times a day.
Child: according to 0.15-0.3 mg / kg of body weight 2-3 times a day.
Transient abdominal pain, intestinal cramps, rumbling, diarrhea, headache, dizziness, arrhythmia, including ventricular tachycardia, ventricular fibrillation, torsades de pointes, QT lengthening, liver failure, pollakiuria (with high doses), allergic reactions (itching, rash, urticaria, bronchospasm).
Increases the tone and motor activity of the gastrointestinal tract, increases the tone of the sphincter of the lower part of the esophagus and prevents the abandonment of the contents of the stomach. Accelerates the emptying of the stomach and duodenum, promoting food in the small intestine and large intestine, prevents food stasis and duodenal-gastric reflux.
- Serotonergic agents
- Stimulants of gastrointestinal motility, including emetics
CYP3A4 inhibitors increase the effect unpredictably. The likelihood of side effects increases antiarrhythmic drugs (classes IA and III), tricyclic antidepressants (amitriptyline) and tetracyclic (Maprotiline), antipsychotics (phenothiazines, pimozide, sertindol) and antihistamines (astemisol, terfenadine).
