Canison plus

Canison plus

Betamethasone Dipropionate, Clotrimazol, Gentamicin Sulfate

Cream for external use

simple and allergic dermatitis (especially complicated by secondary infection),

diffuse neurodermatitis (including atopic dermatitis),

limited neurodermatitis (including simple chronic lichen),

eczema,

dermatomycosis (dermatophytosis, candidiasis, multi-colored lichen), especially when localized in the groin area and large skin folds.

Locally.

A small amount of the drug is applied to the affected areas of the skin, lightly rubbing, 2 times a day. The duration of treatment is determined individually and depends on the nosological form and severity of the disease.

With dermatomycosis of the feet, the average duration of treatment is 2-4 weeks.

If clinical improvement does not occur in the near future, it is necessary to clarify the diagnosis or change the treatment regimen.

hypersensitivity to any of the components of the drug,

tuberculosis of the skin,

cutaneous manifestations of syphilis,

chickenpox,

herpes simplex,

post-vaccination skin reactions,

open wounds,

children's age (up to 2 years).

With caution: pregnancy (especially the first trimester), childhood (from 2 to 18 years).

Itching, burning, irritation, dry skin, folliculitis, hypertrichosis, steroid acne, hypopigmentation, allergic reactions.

When using occlusive dressings-maceration, infection, skin atrophy, striae, sweating.

With prolonged treatment or application to a large surface — the development of systemic side effects: weight gain, osteoporosis, increased blood pressure, edema, ulceration of the gastrointestinal mucosa, exacerbation of hidden foci of infection, hyperglycemia, agitation, insomnia, dysmenorrhea.

Symptoms: phenomena of hypercorticism.

Treatment: gradual withdrawal of the drug. Symptomatic therapy. If necessary — correction of electrolyte disturbances.

The combined drug has anti-inflammatory, anti-allergic, antibacterial and antifungal (fungicidal) effects.

Betamethasone - GCS, has a local anti-inflammatory, anti-edematous, anti-allergic effect.

Gentamicin — a broad-spectrum antibiotic from the group of aminoglycosides, acts bactericidal. Highly sensitive gram-negative microorganisms: Proteus spp. (indole-positive and indole-negative), Escherichia coli, Klebsiella spp., Salmonella spp., Shigella spp., Campylobacter spp., Staphylococcus spp. (methicillin-resistant). Sensitive: Enterococcus faecalis, Serratia spp., Pseudomonas spp., Acinetobacter spp., Citrobacter spp. Resistant: Neisseria meningitidis, Treponema pallidum, anaerobic microbes Streptococcus spp. (except for Streptococcus pneumoniae), Enterococcus faecalis, Providencia rettgeri.

Clotrimazole — antifungal agent from the group of imidazole derivatives for topical use. It has an effect due to the violation of the synthesis of ergosterol, which is an integral part of the cell membrane of fungi. It has a wide spectrum of action. Active against pathogenic dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis), yeast and mold fungi (Candida spp., Torulopsis glabrata, Rhodotorula spp., Pityrosporum orbiculare).

When the drug is applied in therapeutic doses, the transdermal absorption of active substances into the blood is very insignificant. When applied to the skin, the intensity of absorption of betamethasone depends on the state of the epidermal barrier (inflammation and skin diseases increase absorption). The use of occlusive dressings increases the transdermal absorption of betamethasone and gentamicin, which may lead to an increased risk of systemic side effects.

• Glucocorticosteroid for topical use antibiotic-aminoglycoside antifungal agent [Glucocorticosteroids in combinations]

Interaction of the drug with other drugs was not revealed.