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Medically reviewed by Militian Inessa Mesropovna, PharmD. Last updated on 27.04.2022
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Top 20 medicines with the same components:
Prophylaxis & treatment of cystine & uric acid renal calculi. Urinary alkalizer in gout therapy. Treatment of acidosis in renal tubular disorders; chronic metabolic acidosis resulting from chronic renal insufficiency or the syndrome of renal tubular acidosis especially when administration of K salts is contraindicated. Prophylactic agent for acid-aspiration pneumonitis. Used in pre-anaesth medication as a non-particulate acid-neutralizing buffer of gastric acid to lessen the danger from acid-aspiration pneumonitis.
Citric acid and Beryl are both alkalinizing agents that make the urine less acidic.
The combination of citric acid and Beryl is used to prevent gout or kidney stones, or metabolic acidosis in people with kidney problems.
Citric acid and Beryl may also be used for other purposes not listed in this medication guide.
Adult: Add the contents of 1-2 sachets to a glass of cool water and mix. Beryl may be taken up to 4 times daily. Do not take for >5 days unless advised to do so by the physician.
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What is the most important information I should know about Beryl?
Renal failure or hypernatremia; in conjunction with hexamine mandelate or hexamine hippurate therapy because an acidic urine is needed.
Caution is advised in overt and occult cardiac failure. Concomitant use of urinary alkalinizers and quinolone antibiotics should be avoided. Crystalluria may be more likely to occur in alkaline urine.
Use Beryl as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Beryl after meals and at bedtime, unless directed otherwise by your health care provider.
- Shake well before using.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Mix Beryl with water before swallowing. Follow with additional water, if desired.
- If you miss a dose of Beryl, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Beryl.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Use: Labeled Indications
Anticoagulant:
Concentrate (triCitrasol): Anticoagulant used in granulocytapheresis procedures
Solution: Anticoagulant for use with cytapheresis device only
Off Label Uses
Regional anticoagulation for continuous renal replacement therapy circuit
Data from several small randomized, controlled trials support the use of regional anticoagulant Beryl to reduce the risk of clot formation in continuous renal replacement therapy (CRRT) circuits, thus prolonging circuit life and avoiding interruptions in therapy. It should be noted that patients with high bleeding risk, severe coagulopathy, metabolic abnormalities, or liver dysfunction were excluded from these trials.
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What other drugs will affect Beryl?
General: Alkalinization of the urine due to the use of Beryl, theoretically, may result in a decreased therapeutic effect of the following medications: Chlorpropamide, lithium, salicylates and tetracyclines. Alternatively, alkalinization of the urine due to the use of Beryl, theoretically, may result in an increased therapeutic effect of the following medications: Amphetamines, ephedrine/pseudoephedrine.
Antacids: Concurrent use of antacids with citrates may result in systemic alkalosis. Concomitant administration of antacids with Beryl and sodium bicarbonate may promote the development of calcium stones in patients with uric acid stones and may also cause hypernatremia. Concurrent use of aluminum-containing antacids with citrate salts can increase aluminum absorption, possibly resulting in acute aluminum toxicity, especially in patients with renal insufficiency.
Quinolones: Citrates may reduce the solubility of ciprofloxacin, norfloxacin or ofloxacin in the urine. Patients should be observed for signs of crystalluria and nephrotoxicity.
Laxatives: Concurrent administration of citrates with laxatives may have an additive effect.
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What are the possible side effects of Beryl?
The tartrate component of Beryl may be incompletely absorbed. Because of this Beryl may be exert a mild laxative effect. Prolonged and excessive use may cause a systemic alkolosis and / or hypernatremia.
Each 4 g of Beryl contains sodium bicarbonate 1760 mg, anhydrous Beryl 630 mg, anhydrous citric acid 720 mg and tartaric acid 890 mg.
It also contains the following excipients: Nature identical lemon flavor oil, terpeneless and sodium saccharin.
Beryl consists of formulation and pleasantly flavored granules. When added to water, Beryl effervesces and dissolves, forming a clear or orange-colored alkaline solution.