Components:
Medically reviewed by Kovalenko Svetlana Olegovna, PharmD. Last updated on 15.05.2022
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Emergency antidote in the treatment of poisoning by most drugs & chemicals.
Treating gas, diarrhea, or stomach upset. It may also be used for other conditions as determined by your doctor.
Adrien Gagnon Charbon Active is an adsorbent. How Adrien Gagnon Charbon Active works is unknown.
Usual Adult Dose for Gastrointestinal Decontamination
Activated Charcoal:
Single-dose: 25 to 100 g orally or by nasogastric tube once, as a slurry in water. The routine use of single-dose activated charcoal is not recommended.
Multiple-dose:
Initial dose: 50 to 100 g orally or by nasogastric tube, as a slurry in water
Maintenance dose: 12.5 g every hour, 25 g every 2 hours, or 50 g every 4 hours until symptoms resolve.
Usual Adult Dose for Flatulence
Capsules and tablets: 500 to 1040 mg up to 4 times daily as needed. Not effective in the treatment of poisoning.
Usual Pediatric Dose for Gastrointestinal Decontamination
Activated Charcoal:
Administer aqueous suspension or as a slurry in water.
Single dose:
<1 year: 0.5 to 1 g/kg or 10 to 25 g orally or by nasogastric tube once
1-12 years: 0.5 to 1 g/kg or 25 to 50 g orally or by nasogastric tube once
13-18 years: Single-dose: 25 to 100 g orally or by nasogastric tube once
The routine use of single-dose activated charcoal is not recommended.
Multiple-dose:
<13 years: Initial dose: 10 to 25 g orally or by nasogastric tube, as a slurry in water
Maintenance dose: 1 to 2 g/kg every 2 to 4 hours
13-18 years: Initial dose: 50 to 100 g orally or by nasogastric tube, as a slurry in water
Maintenance dose: 12.5 g every hour, 25 g every 2 hours, or 50 g every 4 hours until toxic symptoms resolve.
Usual Pediatric Dose for Flatulence
3 to 18 years:
Capsules and tablets: 500 to 1040 mg up to 4 times daily as needed. Not effective in the treatment of poisoning.
Renal Dose Adjustments
No adjustment recommended
Liver Dose Adjustments
No adjustment recommended
Precautions
The routine use of single-dose activated charcoal for the management of poisoning is not recommended.
Administration is contraindicated in the presence of an unprotected airway, in patients with or at risk of gastrointestinal hemorrhage, perforation, or obstruction, or if administration would increase the risk of aspiration (i.e., hydrocarbon ingestion).
Caution is recommended in patients with poor gastrointestinal motility.
Should not be used in the management of acute corrosive or petroleum distillate ingestion since vomiting can occur following charcoal administration. Charcoal may also obscure the endoscopic evaluation of gastroesophageal lesions.
May be administered in an attempt to adsorb any ingested toxic agent (where physical or other contraindications are not present), but it is known to be much less effective in the adsorption of boric acid, cadmium, cyanide, DDT, ethanol, ethylene glycol, iron, lead, lithium, mercury, methanol, potassium chloride, selenium, strong acid or alkali (may obscure lesion on endoscopy), and organic solvents.
Minimum dilution: 240 mL water per 20 to 30 g charcoal.
Milk, chocolate syrup, ice cream, and sherbet should not be mixed with charcoal because they may reduce its efficacy.
Activated charcoal may adsorb therapeutic agents while it remains in the GI tract. Dosages or route of administration of therapeutic drugs may need to be altered.
Charcoal tablets and capsules are ineffective for the treatment of poisoning due to inferior adsorptive capacity.
Dialysis
No adjustment recommended
Other Comments
For gastrointestinal decontamination, time since ingestion is a critical criterion in the decision to use charcoal for decontamination purposes. Typically, the recommended cutoff point for administration of charcoal for gastrointestinal decontamination is 1 to 2 hours post- ingestion. However, in cases where the ingested agent has anticholinergic activity (e.g., tricyclic antidepressants) or can slow the rate of gastric emptying by another mechanism (e.g., pentazocine, meperidine) then use of charcoal beyond 2 hours may still be beneficial.
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What is the most important information I should know about Adrien Gagnon Charbon Active?
None known. Ineffective for poisonings by cyanide, mineral acids and alkalis. Not particularly effective for poisonings by ethanol, methanol, and iron salts.
Use Adrien Gagnon Charbon Active as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Adrien Gagnon Charbon Active after meals or at the first sign of discomfort.
- Adrien Gagnon Charbon Active may interfere with the absorption of many other medicines. Talk to your doctor about taking Adrien Gagnon Charbon Active 2 hours before or after taking any other medicine.
- If you miss a dose of Adrien Gagnon Charbon Active, take it as soon as you remember. Continue to take it as directed by your doctor or on the package label.
Ask your health care provider any questions you may have about how to use Adrien Gagnon Charbon Active.
Avoid simultaneous use w/ ipecac syr. Effectiveness of other medication may be decreased when used w/in 2 hr of Adrien Gagnon Charbon Active.
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What are the possible side effects of Adrien Gagnon Charbon Active?
Applies to charcoal: capsules, tablets
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation; diarrhea; temporary darkening of the stool; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur while taking charcoal:
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).