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Components:
Thiamine Hydrochloride
Method of action:
Replenishing Vitamin B1 Deficiency, Vitamins
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Medically reviewed by Oliinyk Elizabeth Ivanovna, Pharmacy. Last updated on 2019.09.19

Name of the medicinal product

Actamin 0.1%

Qualitative and quantitative composition

Thiamine Hydrochloride

Therapeutic indications

The information provided in Therapeutic indications of Actamin 0.1% is based on data of another medicine with exactly the same composition as the Actamin 0.1% of the medicine (Thiamine Hydrochloride). Be careful and be sure to specify the information on the section Therapeutic indications in the instructions to the drug Actamin 0.1% directly from the package or from the pharmacist at the pharmacy.
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Treatment of Actamin 0.1% deficiency

Dosage (Posology) and method of administration

The information provided in Dosage (Posology) and method of administration of Actamin 0.1% is based on data of another medicine with exactly the same composition as the Actamin 0.1% of the medicine (Thiamine Hydrochloride). Be careful and be sure to specify the information on the section Dosage (Posology) and method of administration in the instructions to the drug Actamin 0.1% directly from the package or from the pharmacist at the pharmacy.
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Adults, the Elderly and Children over three years:

Mild chronic deficiency: 50mg daily

Severe deficiency: 100mg three times daily.

Not recommended for children under three years.

Route of administration: oral

Contraindications

The information provided in Contraindications of Actamin 0.1% is based on data of another medicine with exactly the same composition as the Actamin 0.1% of the medicine (Thiamine Hydrochloride). Be careful and be sure to specify the information on the section Contraindications in the instructions to the drug Actamin 0.1% directly from the package or from the pharmacist at the pharmacy.
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Special warnings and precautions for use

The information provided in Special warnings and precautions for use of Actamin 0.1% is based on data of another medicine with exactly the same composition as the Actamin 0.1% of the medicine (Thiamine Hydrochloride). Be careful and be sure to specify the information on the section Special warnings and precautions for use in the instructions to the drug Actamin 0.1% directly from the package or from the pharmacist at the pharmacy.
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This medicinal product contains lactose monohydrate. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.

This medicinal product also contains sucrose. Patients with rare hereditary problems of fructose intolerance, malabsorption or sucrose-isomaltase insufficiency should not take this medicine

Effects on ability to drive and use machines

The information provided in Effects on ability to drive and use machines of Actamin 0.1% is based on data of another medicine with exactly the same composition as the Actamin 0.1% of the medicine (Thiamine Hydrochloride). Be careful and be sure to specify the information on the section Effects on ability to drive and use machines in the instructions to the drug Actamin 0.1% directly from the package or from the pharmacist at the pharmacy.
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No studies on the effect on the ability to drive and use machines have been performed. However, patients should be cautioned to see how they react before driving or operating machinery.

Undesirable effects

The information provided in Undesirable effects of Actamin 0.1% is based on data of another medicine with exactly the same composition as the Actamin 0.1% of the medicine (Thiamine Hydrochloride). Be careful and be sure to specify the information on the section Undesirable effects in the instructions to the drug Actamin 0.1% directly from the package or from the pharmacist at the pharmacy.
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Gastrointestinal disorders:

Mild gastrointestinal events such as nausea, vomiting, diarrhoea, and abdominal pain have been reported. Frequency not known (cannot be estimated from data).

Immune system disorders:

Hypersensitivity reactions have been reported (mainly after parenteral administration). Allergic and anaphylactic reactions, with symptoms of pruritus, urticaria, itching, hives, angioedema, abdominal pain, respiratory distress, tachycardia, palpitations, and shock have been reported in single cases. Frequency not known (cannot be estimated from data).

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme; Website: www.mhra.gov.uk/yellowcard.

Overdose

The information provided in Overdose of Actamin 0.1% is based on data of another medicine with exactly the same composition as the Actamin 0.1% of the medicine (Thiamine Hydrochloride). Be careful and be sure to specify the information on the section Overdose in the instructions to the drug Actamin 0.1% directly from the package or from the pharmacist at the pharmacy.
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Overdose has not been reported.

Pharmacodynamic properties

The information provided in Pharmacodynamic properties of Actamin 0.1% is based on data of another medicine with exactly the same composition as the Actamin 0.1% of the medicine (Thiamine Hydrochloride). Be careful and be sure to specify the information on the section Pharmacodynamic properties in the instructions to the drug Actamin 0.1% directly from the package or from the pharmacist at the pharmacy.
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ATC Code: A11DA01

Pharmacotheraputic Group: Vitamin B1, Plain

Actamin 0.1% is an essential co-enzyme for carbohydrate metabolism.

Pharmacokinetic properties

The information provided in Pharmacokinetic properties of Actamin 0.1% is based on data of another medicine with exactly the same composition as the Actamin 0.1% of the medicine (Thiamine Hydrochloride). Be careful and be sure to specify the information on the section Pharmacokinetic properties in the instructions to the drug Actamin 0.1% directly from the package or from the pharmacist at the pharmacy.
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Actamin 0.1% is well absorbed from the gastrointestinal tract following oral administration, although the absorption of large doses is limited. It is widely distributed to most body tissues and appears in breast milk. Within the cell, Actamin 0.1% is mostly present as the diphosphate. Actamin 0.1% is not stored to any appreciable extent in the body; amounts in excess of the body's requirements are excreted in the urine as unchanged Actamin 0.1% or metabolites.

Preclinical safety data

The information provided in Preclinical safety data of Actamin 0.1% is based on data of another medicine with exactly the same composition as the Actamin 0.1% of the medicine (Thiamine Hydrochloride). Be careful and be sure to specify the information on the section Preclinical safety data in the instructions to the drug Actamin 0.1% directly from the package or from the pharmacist at the pharmacy.
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No relevant data

Incompatibilities

The information provided in Incompatibilities of Actamin 0.1% is based on data of another medicine with exactly the same composition as the Actamin 0.1% of the medicine (Thiamine Hydrochloride). Be careful and be sure to specify the information on the section Incompatibilities in the instructions to the drug Actamin 0.1% directly from the package or from the pharmacist at the pharmacy.
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None known

Special precautions for disposal and other handling

The information provided in Special precautions for disposal and other handling of Actamin 0.1% is based on data of another medicine with exactly the same composition as the Actamin 0.1% of the medicine (Thiamine Hydrochloride). Be careful and be sure to specify the information on the section Special precautions for disposal and other handling in the instructions to the drug Actamin 0.1% directly from the package or from the pharmacist at the pharmacy.
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None