Components:
Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 19.06.2022
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Top 20 medicines with the same components:
Respiratory diseases accompanied by the formation of high-viscosity sputum (acute and chronic bronchitis, pneumonia, bronchiectasia, cystic fibrosis, bronchial asthma).
Respiratory diseases accompanied by the formation of high-viscosity sputum (acute and chronic bronchitis, pneumonia, bronchiectasia, cystic fibrosis, bronchial asthma).
Violation of sputum discharge:
bronchitis,
tracheitis,
bronchiolitis,
pneumonia,
bronchiectatic disease,
cystic fibrosis,
lung abscess,
emphysema of the lungs,
laryngotracheitis,
bronchial asthma,
atelectasis of the lung (due to blockage of the bronchi with a mucosal plug),
catarrhal and purulent otitis media,
sinusitis,
sinusitis (relief of discharge of secretions),
removal of viscous secretions from the respiratory tract in post-traumatic and postoperative conditions,
preparation for bronchoscopy, bronchography, aspiration drainage,
for washing abscesses, nasal passages, maxillary sinuses, middle ear, treatment of fistulas, operating field during operations on the nasal cavity and mastoid process.
Diseases of the respiratory system, accompanied by the formation of viscous sputum difficult to separate:
acute and chronic bronchitis,
obstructive bronchitis,
bronchitis, laryngotracheitis,
pneumonia, lung abscess,
bronchiectatic disease,
bronchial asthma, chronic obstructive pulmonary disease,
the bronchiolitis,
cystic fibrosis,
acute and chronic sinusitis,
inflammation of the middle ear (otitis media).
Difficult sputum separation (bronchitis, pneumonia, bronchiectatic disease), bronchial asthma, cystic fibrosis of the lungs, complications during operations on the respiratory organs (prevention).
Acute and chronic diseases of the bronchopulmonary system, accompanied by viscous and thick sputum: bronchitis (including asthmatic), tracheobronchitis, pneumonia, bronchiectasis, emphysema, tuberculosis and amyloidosis of the lungs, atelectasis due to blockage of the bronchi with mucus, pulmonary complications (postoperative, post-traumatic, cystic fibrosis), diagnostic studies of the bronchi, prevention and reduction of paracetamol hepatotoxicity (acetaminophen).
V/v, v/m.
In the absence of other prescriptions, it is recommended to adhere to the following dosages.
Adults: 1 amp. containing 300 mg of acetylcysteine, i / v or i/m 1-2 times a day.
Children aged 6 to 14 years: 1/2 amp. (150 mg of acetylcysteine) i / v or i / m 1-2 times a day .
Children under 6 years of age: as a rule, oral therapy is preferred.
Children under one year of age: intravenous administration of acetylcysteine is possible only for vital indications in a hospital setting.
In the event that there are still indications for parenteral therapy, the daily dose for children under 6 years of age should be 10 mg/kg.
Type and duration of application
In/m therapy: it is recommended to administer the drug to patients in a supine position and deep into the muscle.
IV therapy: For intravenous administration, the drug is used in the intensive care unit and only in the case when it is impossible to use dosage forms of acetylcysteine for oral administration. The first dose should be diluted with 0.9% sodium chloride solution or 5% glucose solution in a ratio of 1:1. If possible, subsequent doses are administered in the form of infusions. Intravenous injections should be administered slowly (within 5 minutes). The duration of therapy is determined individually and usually is no more than 10 days.
In chronic bronchitis and cystic fibrosis, it is possible to use acetylcysteine for a long time with the use of oral forms for the prevention of infections.
Indication: the mucolytic effect of acetylcysteine increases with increased fluid intake.
Inside. Adults — 200 mg 2-3 times a day in the form of a granulate. Children 2-6 years — 200 mg 2 times a day or 100 mg 3 times a day in the form of water-soluble granulate, younger than 2 years-100 mg 2 times a day, 6-14 years-200 mg 2 times a day. For chronic diseases for several weeks: adults-400-600 mg/day in 1-2 doses, children 2-14 years-100 mg 3 times a day, for cystic fibrosis: children from 10 days to 2 years — 50 mg 3 times a day, 2-6 years-100 mg 4 times a day, over 6 years-200 mg 3 times a day in the form of water-soluble granulate.
The duration of therapy is determined individually (no more than 10 days). In patients over 65 years of age, the minimum effective dose is used.
Inside, after eating, first dissolve the powder in a glass of water.
The following dosages are usually recommended: adults and adolescents over 14 years of age — 400-600 mg/day, in 2-3 doses, newborns (only for vital indications) - at a dose of 10 mg / kg under strict medical supervision. Children of the first year of life-are given to drink the resulting solution from a spoon or bottle for feeding, children from 1 to 2 years (only under strict medical supervision) — 100-200 mg/day in 2-3 doses, 2-6 years-200 mg/day in 2-3 doses, older than 6 years-400 mg/day in 2-3 doses.
Treatment of cystic fibrosis: infants from day 10 and children under 2 years — 100-150 mg/day in 2-3 doses (under strict medical supervision), children 2-6 years-400 mg/day in 4 doses, older than 6 years-600 mg/day in 3 doses.
The duration of continuous use depends on the characteristics of the course of the disease. In the treatment of chronic bronchitis and cystic fibrosis, treatment can be prolonged (up to several months).
Inside, after eating, without chewing, with a sufficient amount of liquid or dissolved in a glass of water. The duration of treatment is set individually.
100 mg tablets: adults and children from 14 years — 2 tables 2-3 times a day, children 6-14 years — 1 table 3-4 times a day, 2-5 years-1 table 2-3 times a day. For cystic fibrosis: children from 2 to 6 years — 1 table. 4 times a day.
200 mg tablets: adults and children from 14 years — 2 tables 2-3 times a day, children 6-14 years - 1 table. 2 times a day. For cystic fibrosis: children over 6 years of age - 1 table. 3 times a day.
600 mg tablets: adults and children from 14 years — 1/2 table. 2 times a day or 1 table. 1 time a day.
Inside, after meals, tablets effervescent tablets should be dissolved in one glass of water and taken after meals. Tablets should be taken immediately after dissolution, in exceptional cases, you can leave the solution ready for use for 2 hours.Additional liquid intake increases the mucolytic effect of the drug.
For short-term colds, the duration of administration is 5-7 days.
In chronic bronchitis and cystic fibrosis, the drug should be taken for a longer time to achieve a preventive effect.
In the absence of other prescriptions for mucolytic therapy, it is recommended to adhere to the following dosages: adults and children over 14 years of age - 1 table of effervescent 1 time a day (600 mg).
Inhaled, 2-5 ml of 20% solution for 15-20 minutes.
Inhalation, instillation and oral administration (not applicable for injection). Bronchopulmonary diseases and conditions with hypersecretion: inhaled 3-5 ml of 20% or 6-10 ml of 10% solution (can be diluted with sterile water or sodium chloride solution for injection up to 5%) 3-4 times a day (if necessary, 1-10 ml of 20% or 2-20 ml of 10% solution every 2-6 hours), instillation-intratracheal 1-2 ml of 20% solution after 1-4 hours. Diagnostic tests: inhalation or endobronchial instillation of 1-2 ml of 20% (2-4 ml of 10%) solution 2-3 times before the procedure. Overdose of paracetamol: inside or duodenally-after preliminary emptying of the stomach, first 140 mg/kg of body weight 1 time, then 70 mg/kg 17 times every 4 hours (under daily laboratory complex control of the liver and blood), dilute the 20% solution with a liquid that does not contain carbohydrates to 5%
hypersensitivity,
pregnancy,
lactation period.
With caution:
peptic ulcer of the stomach and duodenum (in the acute phase),
varicose veins of the esophagus,
hemoptysis,
pulmonary hemorrhage,
phenylketonuria (for forms containing aspartame),
bronchial asthma (with intravenous administration, the risk of developing bronchospasm),
diseases of the adrenal glands,
hepatic and / or renal insufficiency,
arterial hypertension.
hypersensitivity to acetylcysteine or other components of the drug,
peptic ulcer of the stomach and duodenum in the acute stage,
hemoptysis, pulmonary hemorrhage,
lactase deficiency, lactose intolerance, glucose-galactose malabsorption,
pregnancy,
breastfeeding period,
children's age (up to 14 years).
With caution: a history of gastric and duodenal ulcers, esophageal varicose veins, bronchial asthma, obstructive bronchitis, adrenal diseases, hepatic and/or renal insufficiency, histamine intolerance (long-term use of the drug should be avoided, since acetylcysteine affects the metabolism of histamine and can lead to signs of intolerance, such as headache, vasomotor rhinitis, itching), arterial hypertension hypertension.
Hypersensitivity, bronchial asthma with normal sputum discharge.
Hypersensitivity.
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Do not use Acc-Akut 600 inhalation at home if you do not fully understand all instructions that are specific to your use of this medicine.
Acc-Akut 600 inhalation solution can be inhaled directly from the nebulizer or with a face mask, mouth piece, tent, or intermittent positive pressure breathing (IPPB) machine.
Use only the inhaler device provided with your medicine or you may not get the correct dose.
Do not place this medicine directly into a heated nebulizer medicine chamber.
Do not mix your dose of Acc-Akut 600 inhalation until you are ready to use the medicine. Diluted Acc-Akut 600 inhalation must be used within 1 hour of mixing.
Acc-Akut 600 inhalation liquid may change color once you have opened the bottle. This is caused by a chemical reaction and will not affect the medicine.
You may sense an unusual or unpleasant smell while using Acc-Akut 600 inhalation. This effect should become less noticeable the longer you use the medicine.
Clean your nebulizer right after each use. The residue from Acc-Akut 600 inhalation can clog the parts of the nebulizer.
Store an unopened vial (bottle) of Acc-Akut 600 inhalation at room temperature, away from moisture and heat.
An opened Acc-Akut 600 vial should be stored in a refrigerator, but you must use it within 96 hours (4 days) after opening. Do not allow the medicine to freeze.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.When inhaled by mouth, Acc-Akut 600 is used to help thin and loosen mucus in the airways due to certain lung diseases (such as emphysema, bronchitis, cystic fibrosis, pneumonia). This effect helps you to clear the mucus from your lungs so that you can breathe easier.
When taken by mouth, Acc-Akut 600 is used to prevent liver damage from acetaminophen overdose.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This drug may also be taken by mouth to prevent kidney damage due to dyes from certain X-ray procedures (such as CT scan).
How to use Acc-Akut 600 (bulk)
If you are using this medication to treat lung disease, inhale this medication by mouth as directed by your doctor. A health care professional will show you the proper way to use this medication. Learn all preparation and usage instructions.
You may notice a slight odor when you first breathe in the medication. This odor will quickly go away. If you are using a face mask to breathe in the medication, there may be some stickiness on your face after use. Wash your face with water to remove the stickiness.
Do not mix Acc-Akut 600 with other inhaled medications unless directed by the doctor or pharmacist.
If you are taking this medication by mouth, take it as directed by your doctor. The solution is usually mixed with another liquid (such as cola) to decrease nausea and vomiting. Drink the medication within 1 hour of mixing.
Tell your doctor if you vomit within 1 hour after taking your medication. You may need to take another dose.
The dosage is based on your medical condition and response to treatment. For acetaminophen overdose, the dosage is also be based on your weight.
Tell your doctor if your condition does not improve or if it worsens.
See also:
What other drugs will affect Acc-Akut 600?
With simultaneous use of antacids containing magnesium and / or aluminum hydroxide, slow down and reduce the absorption of acetylsalicylic acid.
With simultaneous use of calcium channel blockers, means limiting intake of calcium or increasing the excretion of calcium from the body, increases the risk of bleeding.
With simultaneous use with acetylsalicylic acid enhances the action of heparin and indirect anticoagulants, hypoglycemic funds derived sulfonylureas, insulin, methotrexate, phenytoin, valproic acid.
With simultaneous use of Acc-Akut 600 Millet Roux Produtos Farmaceuticos with SCS increases the risk of ulcerogenic effect and occurrence of gastrointestinal bleeding.
With simultaneous use of decreasing the effectiveness of diuretics (spironolactone, furosemide).
With simultaneous use of other NSAIDs increases the risk of side effects. Acetylsalicylic acid may reduce plasma concentrations indomethacin, piroxicam.
With simultaneous use of gold drugs acetylsalicylic acid can induce liver damage.
With simultaneous use decreases effectiveness of uricosuric medications (including probenecid, sulfinpirazon, benzbromarone).
With simultaneous use of acetylsalicylic acid and alendronate sodium may develop severe esophagitis.
With simultaneous use of griseofulvin may be in breach Absorption of acetylsalicylic acid.
There is one case of spontaneous hemorrhage in the iris while taking Ginkgo Biloba extract on the background of prolonged use of aspirin in a dose of 325 mg / day. It is believed that this may be due to additive inhibitory effect on platelet aggregation.
With simultaneous use of dipyridamole may increase Cmax of salicylate in plasma and AUC.
When applied simultaneously with acetylsalicylic acid increased concentration of digoxin, barbiturates and lithium salts in the blood plasma.
With simultaneous use of salicylates in high doses with carbonic anhydrase inhibitors can intoxication salicylates.
Acetylsalicylic acid in doses of less than 300 mg have little effect on the effectiveness of captopril and enalapril. When aspirin (acetylsalicylic acid) is admistered in high doses may decrease the effectiveness of captopril and enalapril.
With simultaneous application of caffeine increases the rate of absorption, plasma concentrations and bioavailability of acetylsalicylic acid.
With simultaneous use of Acc-Akut 600 Millet Roux Produtos Farmaceuticos with metoprolol may increase Cmax of salicylate in blood plasma.
In the application of pentazocine on the background of long-term use of aspirin in high doses there is a risk of severe adverse reactions in the kidneys.
With simultaneous application phenylbutazone reduces uricosuria caused by acetylsalicylic acid.
With simultaneous application of ethanol may exacerbate the effects of acetylsalicylic acid on the gastrointestinal tract.
Nausea, vomiting, feeling of full stomach, nosebleeds, urticaria, tinnitus, drowsiness, fever. Rarely-dyspepsia (including heartburn). With aerosol therapy: reflex cough, respiratory tract irritation, rhinorrhea, rarely-stomatitis. With intravenous administration-burning at the injection site, with prolonged treatment-impaired liver and/or kidney function.
Adverse effects are listed according to the WHO classification by frequency as follows: very common (≥1/10), common (≥1/100, <1/10), infrequent (≥1/1000, <1/100), rare (≥1/10000, <1/1000) and very rare (<1/10000), frequency unknown (frequency of occurrence cannot be determined based on available data).
Allergic reactions: infrequently-skin itching, rash, exanthema, urticaria, angioedema, decreased blood pressure, tachycardia, very rarely-anaphylactic reactions up to anaphylactic shock, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome).
From the respiratory system: rarely-shortness of breath, bronchospasm (mainly in patients with hyperreactivity of the bronchi in bronchial asthma).
On the part of the senses: infrequently-tinnitus.
From the gastrointestinal tract: infrequently-stomatitis, abdominal pain, nausea, vomiting, diarrhea, dyspepsia.
Other: very rarely-headache, fever, isolated reports of bleeding due to the presence of hypersensitivity reactions, decreased platelet aggregation.
Nausea.
Stomatitis, nausea, vomiting, fever, nasal discharge, chest tightness, bronchospasm, skin allergic reactions.
Symptoms: in case of an erroneous or deliberate overdose, such phenomena as diarrhea, vomiting, stomach pain, heartburn and nausea are observed.
Treatment: symptomatic.
Acetylcysteine
However, we will provide data for each active ingredient