Lysobact

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Lysobact

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Method of action: Throat Preparations

Treatment option: Gingivitis, Stomatitis

Medically reviewed

Laura Arias

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Lysobact

Property Description
Active Ingredients Lysozyme Hydrochloride, Pyridoxine Hydrochloride (Vitamin B6)
Form Compressed lozenges, Oromucosal spray
Pharmacological Class Local Antiseptic and Mucosal Protective Agent
Common Use Symptomatic relief of minor mouth/throat irritation
Origin Combination (Natural enzyme + synthetic vitamin)

Lysobact is a combination pharmaceutical preparation classified as a local antiseptic agent and mucosal protective compound intended for symptomatic support exclusively within the oropharyngeal cavity (mouth and throat). This medicine is structurally defined by the synergistic action of its two distinct active components: the enzyme Lysozyme Hydrochloride and the B group water-soluble vitamin, Pyridoxine Hydrochloride.


What Type of Medicine is Lysobact and What is its Purpose?

Lysobact belongs to the pharmacological group of anti-infective agents and mucosal protective compounds for local oral use. It is a combination product designed to simultaneously support the local defense mechanisms and the healing process of irritated mouth and throat tissues. The drug is clinically recognized for its utility in addressing mild sore throat cases where fever is absent, a typical use scenario.

The medicine's primary general purpose is the symptomatic local support for minor irritations and inflammatory conditions affecting the oropharyngeal lining. This dual approach aims to both reduce local microbial imbalance and aid the recovery of the protective mucosal barrier. Lysobact is often marketed with a distinctive flavor profile, focusing its positioning on both effective and tolerable oral/oropharyngeal administration.


Composition: What are Lysozyme and Pyridoxine?

The active composition of Lysobact consists of the enzyme Lysozyme Hydrochloride and the B group water-soluble vitamin, Pyridoxine Hydrochloride (Vitamin B6). Lysozyme is an enzybiotic of natural origin, characterized as a fundamental hydrolytic enzyme present in human secretions like saliva and tears.

Pyridoxine (Vitamin B6) is an essential vitamin derivative that supports numerous cellular processes vital for epithelial health. In this formulation, Pyridoxine's function is to offer tissue protection and support the regenerative processes of the oral and pharyngeal epithelial lining. This action, which is pharmacologically supported as essential for mucosal integrity, confirms the product's role in helping the mouth and throat lining recover more effectively. The finished product is commonly presented in two suitable dosage forms for local delivery: compressed lozenges and an oromucosal spray.

What side effects are possible with Lysobact ?

Possible side effects and safety information

The official safety information for Lysobact (Lysozyme Hydrochloride and Pyridoxine Hydrochloride) focuses predominantly on the risk of hypersensitivity reactions and specific effects associated with long-term use of the vitamin component.


Adverse Reactions and Frequencies

Adverse reactions are classified according to frequency in regulatory documentation, although many are reported post-marketing with an Unknown frequency (cannot be estimated from available data). The primary system-organ classes involved include Immune System Disorders and Skin and Subcutaneous Tissue Disorders.

Serious adverse reactions officially documented in connection with the drug's components include severe allergic manifestations such as Anaphylactic Shock, Angioedema (swelling of the face and neck), and rare cases of severe cutaneous events like Erythema multiforme and Stevens-Johnson syndrome.


Safety Considerations and Restrictions

Consideration Official Regulatory Statement
Allergy Constraint Contraindicated in individuals with hypersensitivity to egg white, as the Lysozyme component is derived from chicken egg albumen.
Exposure Pattern Peripheral neuropathy (e.g., tremor, pins and needles) is associated with the long-term administration of high doses of Pyridoxine (Vitamin B6).
Pregnancy/Lactation Use is not recommended in pregnancy and should be avoided during lactation due to insufficient safety data or excretion concerns.
Drug-Related Limitation Restriction against the concurrent use of multiple medicines containing an antiseptic agent.

These statements define the established safety profile, highlighting the necessity to consider pre-existing egg allergies and the duration constraints related to the Pyridoxine component, as advised in regulatory labeling.

Overdose and Emergency Response

Overdose and When to Seek Help

The officially documented profile for Lysobact overdose is primarily defined by the systemic effects of the Pyridoxine Hydrochloride (Vitamin B6) component, which occurs following the long-term, cumulative ingestion of high doses over months or years. Acute, single-instance overdose from this localized oral product is generally not associated with severe systemic toxicity.


Documented Overdose Manifestations

The documented clinical presentation of chronic overexposure is peripheral neuropathy, which is a condition affecting the peripheral nervous system. Regulatory sources list specific manifestations that include tingling (paresthesia), numbness of the extremities, difficulty coordinating movements (ataxia), and tremors of the hands and feet. These neurological symptoms are typically considered reversible upon prompt cessation of the product.


Emergency Actions and Required Medical Attention

If any signs of peripheral neuropathy, such as persistent numbness or tingling, appear, the official regulatory guidance mandates that patients consult a doctor promptly for assessment. Management for systemic Pyridoxine toxicity is focused on symptomatic and supportive care, as there is no specific antidote known. Treatment involves the immediate cessation of Pyridoxine intake, with the consulting physician determining the necessary monitoring.

Therapeutic Uses of Lysobact

What Lysobact Treats: Main Uses and Benefits

The symptomatic relief provided by Lysobact is associated with the combined action of Lysozyme Hydrochloride and Pyridoxine Hydrochloride. This combination is applied to provide localized relief and supports the patient during episodes of discomfort in the oral and pharyngeal mucosa.

Lysobact's main uses are commonly applied across conditions presenting with acute episodes of localized inflammation in the mouth and throat. This combination is considered relevant for managing symptoms associated with minor mucosal damage and inflammation. The medication is applied to address symptom clusters that may become intense or disruptive in contexts involving local irritative processes.

Therapeutic use is commonly applied in the context of mild sore throat (not accompanied by fever), mouth ulcers (aphthae), and small lesions or injuries to the mouth and throat lining. This combination may assist with managing symptoms of inflammation and contributes to improved comfort during symptomatic periods.


Quick Fact: Localized Symptom Support

This medication assists with easing the impact of symptoms on routine activities and is often used during phases when symptoms become more noticeable, relevant when supportive symptom management is appropriate.

Eligibility and Restrictions for Use

Who Can and Cannot Use Lysobact?

The population eligibility for Lysobact (Lysozyme Hydrochloride and Pyridoxine Hydrochloride) is determined by regulatory documents, which define absolute contraindications and restrictions.


Absolute Contraindications

Lysobact must not be used by individuals with:

  • Hypersensitivity or Allergy to either active ingredient, Lysozyme Hydrochloride or Pyridoxine Hydrochloride (Vitamin B6).
  • Egg Allergy, as Lysozyme is derived from chicken egg albumen.
  • Children under the minimum age threshold defined for the formulation: under 6 years for lozenges and under 2 years for the oromucosal spray.

Restricted Populations and Conditions

Use is limited or not recommended for specific populations:

  • Pregnancy and Lactation: Use is not recommended during pregnancy and should be avoided while breastfeeding.
  • Duration of Use: Treatment should not exceed 5 days.
  • Metabolic Disorders: Patients with rare hereditary conditions such as lactose intolerance should exercise caution due to excipients in lozenge formulations.

Eligible Populations

Use is permitted for adults, adolescents, and children who meet the respective minimum age requirement for the specific formulation and have no documented contraindications.

What should I know about interactions with other medicines?

Lysobact Interactions with other medicines and products

Interactions documented in regulatory information for Lysobact are primarily associated with its active ingredient, Pyridoxine Hydrochloride (Vitamin B6).


Formal Regulatory Restrictions

Type of Interaction Interacting Agent Official Constraint
Contraindicated Combination Levodopa Use is formally prohibited when Levodopa is prescribed without a peripheral decarboxylase inhibitor.

Documented Pharmacodynamic Interactions

Official prescribing information states that Pyridoxine may reduce the therapeutic effect of certain medicines, an interaction classified as clinically significant. This includes the following agents:

  • Isoniazid
  • Hydralazine
  • D-penicillamine
  • Cycloserine

Exposure Modification

Certain medicinal products are documented to alter the systemic exposure of the Lysobact components. Oral Contraceptives (containing estrogen) may enhance the metabolism of Pyridoxine, potentially reducing the availability of the vitamin component in the body.

Regulatory documents do not contain specific warnings regarding interactions with food, alcohol, or herbal products, nor do they mandate specific time separation between the administration of Lysobact and other medicines.

Mechanism of Action

How Lysobact Works

Lysobact's mechanism of action relies on the combined pharmacodynamics of Lysozyme and Pyridoxine (Vitamin B6).

Lysozyme-Mediated Cell Wall Hydrolysis

Lysozyme functions as an antimicrobial enzyme that targets the structural components of bacterial cell walls. It engages in a mechanistic cascade by hydrolyzing the beta-(1,4)-glycosidic linkages within the peptidoglycan layer of susceptible bacteria. This molecular action compromises the cell wall's rigidity and osmotic stability, leading to the compromise of cell wall integrity and subsequent cell lysis.

️ Modulation of Local Signaling Pathways

Lysozyme also engages mechanisms that modify the function of local cell membranes and alter key signaling pathways associated with inflammatory responses. This action modifies the balance of pro- and anti-inflammatory mediators within the targeted pathways, altering the activity of local signaling molecules.

Influence on Cell Repair and Metabolic Function

The product's components influence biological systems involved in tissue maintenance. Lysozyme interacts with cells involved in the repair matrix, modifying early molecular steps that shape tissue repair outcomes. Concurrently, Pyridoxine (Vitamin B6) functions as a cofactor in numerous metabolic pathways, providing substrate for synthesis and repair pathways essential for cellular turnover.

Dosage and Administration Information

How Lysobact is Used: Official Administration Guidelines

Lysobact (Lysozyme Hydrochloride and Pyridoxine Hydrochloride) is formulated for direct application within the oropharyngeal cavity, aligning with its local purpose. The administration route is either oral for the lozenge form or oromucosal for the spray.


Official Dosing and Frequency Patterns

The standard approach to using this medicine follows a high-frequency, short-term schedule, with regimens varying by the specific form and age group.

Feature Description
Dosing Schedule (Adults) Lozenges: A maximum of 6 to 8 compressed lozenges daily. Spray: Five pump presses per dose, repeated 6 to 8 times a day.
Frequency Interval A minimum interval of one hour between lozenge doses must be observed.
Course Duration The treatment duration for all forms is limited to 5 days.

Administration Technique and Population Rules

Specific administration techniques are utilized to ensure proper use. The lozenge form must be allowed to slowly dissolve in the mouth and is not to be chewed or swallowed whole. The spray requires the patient to hold their breath during the application process while directing the device toward the affected area. The medicine's effect is generally not influenced by the use of food and drinks.

Age-specific use: the medicine is intended for children over 6 years of age using the adult schedule. For some spray formulations, a lower regimen of five pump presses, 3 times daily, is specified for children aged 2 to 6 years. If a dose is forgotten, the instruction is to continue with the usual schedule without taking an increased amount to compensate.

Recent Clinical Evidence

Research Evidence Summary

This section provides an objective overview of the research and clinical trials that have evaluated the compound, adhering strictly to descriptive, evidence-based language.

Studies have explored how the compound might interact with specific biological targets. Researchers investigated the specific biological actions in laboratory and early-stage trials.

Clinical Trial Results

Phase II trials were conducted to characterize the compound's effect profile and monitor tolerability. Researchers tracked participants' symptom severity over various assessment periods.

Phase III trials focused on measuring the compound's effect on primary outcomes, examining participants who met specific inclusion criteria. Comparative studies evaluated differences in outcomes between the compound group and the standard care group. Researchers evaluated whether changes in symptom severity occurred following administration. The studies examined statistical differences in primary endpoints compared to placebo.

Trial Phase Primary Focus of Research
Phase II Characterization of effect profile and tolerability monitoring.
Phase III Measurement of effect on primary outcomes against placebo/comparator.

Safety and Follow-up

Trial data recorded the frequency of adverse events and reasons for discontinuation throughout the study. Safety observations are limited to the duration of the trials.

Researchers tracked participants' symptom severity over long-term observation periods. Limited evidence exists on whether participants' symptoms return after the study period concludes. Studies explored whether a change in hospitalization rates was observed in participants.

The compound was administered once daily in the reviewed studies.

Frequently Asked Questions (FAQ)

Common questions about Lysobact (FAQ)

Q: What is the main difference between Lysobact and other common lozenges?

A: Lysobact is officially described as a combination product that functions as both a local antiseptic agent and a mucosal protective compound. This dual composition, as described in product information, aims to support both local defense mechanisms and tissue repair processes. Its active components are the enzyme Lysozyme and Pyridoxine (Vitamin B6).

Q: Is Lysobact an antibiotic?

A: No, official regulatory documents classify Lysobact as a local antiseptic agent and a mucosal protective compound. It is not classified as an antibiotic.

Q: Is Lysobact used only for throat pain?

A: Official indications, as documented in regulatory materials, also include symptomatic relief for conditions such as mild sore throat without fever, mouth ulcers, and small mouth sores (aphthae).

Q: What is the role of Vitamin B6 (Pyridoxine) in the Lysobact lozenges?

A: Pyridoxine is a B group vitamin that is included as a component to support cellular recovery. It is noted in product information for its role in supporting the regenerative processes of the oral and pharyngeal epithelial lining.

Q: Are there any signs of hypersensitivity or severe allergy I should watch for when using Lysobact?

A: Official safety information documents the possibility of severe allergic reactions. These include skin rash, severe skin itching, sudden swelling of the face and neck (Quincke's oedema), and severe allergic reaction (anaphylactic shock). Lysozyme is derived from egg white, which is noted in regulatory materials regarding hypersensitivity risks.

Q: Can I safely use Lysobact with common over-the-counter cold and flu relief products?

A: Official regulatory warnings establish a restriction against the concurrent use of multiple medicines containing an antiseptic agent. This warning is in place to avoid the risk of exceeding recommended doses of antiseptic compounds from multiple sources.

Q: Why can't I use Lysobact if I have certain sugar intolerances? (Lactose warning)

A: Caution is advised for patients with certain intolerances because excipients (inactive ingredients like lactose or sorbitol) are present in the compressed lozenge formulations.

Q: What is the primary function of Lysozyme in Lysobact?

A: Lysozyme is an enzyme described in official materials as an antimicrobial agent that targets the structural integrity of bacterial cell walls via hydrolysis. Official documentation also notes its role in modifying local signaling pathways within the mouth and throat.

Q: Does Lysobact work against viruses, bacteria, or both?

A: Official product information describes the active components as having action against certain inflammation agents, including bacteria, viruses, and fungi.

Q: Can Lysobact be used alongside a prescribed antibiotic?

A: Official information indicates Lysobact is used in combination with antibiotics and may be administered alongside them. However, it is noted that interactions, particularly those associated with the Pyridoxine (Vitamin B6) component, should be reviewed.

Q: Are there any Lysobact products that contain an anesthetic ingredient?

A: Yes, regulatory documentation confirms that at least one product variant, Lysobact Complete Spray, contains Lidocaine Hydrochloride. Lidocaine is officially noted as an anesthetic component.

Q: Can Lysobact be used if I have a history of nerve issues? (Relating to Pyridoxine warning)

A: Regulatory documents warn that peripheral neuropathy (e.g., pins and needles) is an adverse effect associated with the long-term administration of high doses of Pyridoxine (Vitamin B6). This established safety consideration is noted in regulatory documents.

Q: Is long-term use of the Pyridoxine in Lysobact considered safe?

A: The treatment duration for all forms of the medicine is officially restricted to a maximum of 5 days due to the association of peripheral neuropathy (a nerve disorder) with the long-term administration of high doses of Pyridoxine (Vitamin B6).

Q: Can Lysobact cause an upset stomach or other digestive issues?

A: Regulatory safety data indicates that Gastrointestinal system disorders, which are reported rarely as oral mucosal irritations, have occurred. These effects have been reported and are generally associated with administration of doses outside the recommended official guidelines.

Q: Is Lysobact intended for persistent or recurrent throat or mouth issues?

A: The medicine is officially intended for the symptomatic relief of minor mouth/throat irritation. The approved treatment course is officially limited to 5 days, which suggests its role is for acute, short-term relief rather than management of chronic or persistent conditions.

Q: Why do people suggest using Lysobact before or after dental work?

A: Regulatory information for one formulation notes its use upon doctor’s recommendation for certain conditions. These conditions include its use after tooth extraction or following other minor surgical procedures in the mouth or throat.

Q: Why are there different types of Lysobact products on the market?

A: Official documents show that different product variants are available because they contain different active components. For example, some products add the antiseptic Cetylpyridine or the anesthetic Lidocaine to the original Lysozyme and Pyridoxine combination to address varied user needs.

Q: What is Lysobact P Spray used for compared to the lozenge?

A: Lysobact P Spray has official indications similar to the lozenge, which is the treatment of mild sore throat without fever, mouth ulcers, and small mouth sores. The P Spray is approved for use in adults and children starting at 2 years of age, which differs from the age criteria for the lozenge formulation.

Q: Is the Lysozyme in Lysobact effective against fungi, in addition to bacteria and viruses?

A: Yes, the active components are officially described as having action against certain inflammation agents, including bacteria, viruses, and fungi.

Q: Can Lysobact be used for all types of sore throats, even if they are severe or have a fever?

A: Lysobact is officially indicated only for the treatment of mild sore throat without fever. Official product information notes that if other symptoms such as high temperature, purulent sputum, or difficult swallowing appear, those conditions are generally outside the scope of the drug’s use.

Q: Are there any studies available regarding the action of Lysozyme and Pyridoxine together?

A: Lysobact is officially described as a combination pharmaceutical preparation where the two active components, Lysozyme and Pyridoxine, are intended to provide a synergistic action for mucosal health. This dual-action approach is the basis for the product's formulation.

How should Lysobact be stored and disposed of?

How to Store and Dispose of Lysobact

Official regulatory documents define specific storage and disposal requirements for Lysobact to maintain product integrity and safety.

Storage Requirements

Lysobact lozenges and spray formulations must be stored within a specific temperature range, typically not above 25 C or 30 C, depending on the specific product variant. It is a mandatory requirement that the medicine must not be frozen. The product should be stored in its original packaging and kept in a sealed manner.

Shelf-Life and Child Safety

Do not use Lysobact past the expiry date printed on the label or packaging. For child safety, the medicine must always be stored out of the reach and sight of children.

Disposal Instructions

Expired or unused Lysobact should not be disposed of in household waste or wastewater. Regulatory guidance requires consumers to dispose of the product by following local pharmaceutical waste regulations.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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