×
Components:
Hydrocortisone
Method of action:
Antiallergic, Antiexudative, Antihemorrhoidal, Anti-Inflammatory, Antipruritic, Anti-Shock, Corticosteroids For Systemic Use, Corticosteroids, Dermatological Preparations, Desensitizing, Glucocorticoid, Weak
Available in countries
See all
close
Medically reviewed by Kovalenko Svetlana Olegovna, PharmD. Last updated on 2019.10.20

Name of the medicinal product

Acortine

Qualitative and quantitative composition

Hydrocortisone

Pharmaceutical form

Cream

Therapeutic indications

The information provided in Therapeutic indications of Acortine is based on data of another medicine with exactly the same composition as the Acortine of the medicine (Hydrocortisone). Be careful and be sure to specify the information on the section Therapeutic indications in the instructions to the drug Acortine directly from the package or from the pharmacist at the pharmacy.
more... close

Acortine Cream is indicated in adults, children and infants.

Dosage (Posology) and method of administration

The information provided in Dosage (Posology) and method of administration of Acortine is based on data of another medicine with exactly the same composition as the Acortine of the medicine (Hydrocortisone). Be careful and be sure to specify the information on the section Dosage (Posology) and method of administration in the instructions to the drug Acortine directly from the package or from the pharmacist at the pharmacy.
more... close

Posology

Adults and older people

The same dose is used for adults and older people, as clinical evidence would indicate that no special dosage regimen is necessary in older people.

Paediatric population

Long term treatment should be avoided where possible.

Infants

Therapy should be limited if possible to a maximum of seven days.

Method of administration

For cutaneous use.

Dosage: To be applied evenly and sparingly no more than twice daily.

Application may be made under occlusion in the more resistant lesions such as thickened psoriatic plaques on elbows and knees.

Contraindications

The information provided in Contraindications of Acortine is based on data of another medicine with exactly the same composition as the Acortine of the medicine (Hydrocortisone). Be careful and be sure to specify the information on the section Contraindications in the instructions to the drug Acortine directly from the package or from the pharmacist at the pharmacy.
more... close

This preparation is contraindicated in the presence of untreated viral or fungal infections, tubercular or syphilitic lesions, peri-oral dermatitis, acne vulgaris and rosacea and in bacterial infections unless used in connection with appropriate chemotherapy.

Special warnings and precautions for use

The information provided in Special warnings and precautions for use of Acortine is based on data of another medicine with exactly the same composition as the Acortine of the medicine (Hydrocortisone). Be careful and be sure to specify the information on the section Special warnings and precautions for use in the instructions to the drug Acortine directly from the package or from the pharmacist at the pharmacy.
more... close

Application under occlusion should be restricted to dermatoses involving limited areas.

As with all corticosteroids, application to the face, flexures and other areas of thin skin may cause skin atrophy and increased absorption and should be avoided.

Topical corticosteroids may be hazardous in psoriasis for a number of reasons including rebound relapses following development of tolerance, risk of generalised pustular psoriasis and local and systemic toxicity due to impaired barrier function of the skin. Steroids may have a place in psoriasis of the scalp and chronic plaque psoriasis of the hands and feet. Careful patient supervision is important.

The cetostearyl alcohol may cause local skin reactions (e.g contact dermatitis) and the butyl and propyl parahydroxybenzoate may cause allergic reactions which can be delayed.

Infants

Although generally regarded as safe, even for long-term administration in adults, there is a potential for adverse effects if over used in infancy. Extreme caution is required in dermatoses of infancy including napkin eruption. In such patients courses of treatment should not normally exceed 7 days.

Keep away from the eyes.

Effects on ability to drive and use machines

The information provided in Effects on ability to drive and use machines of Acortine is based on data of another medicine with exactly the same composition as the Acortine of the medicine (Hydrocortisone). Be careful and be sure to specify the information on the section Effects on ability to drive and use machines in the instructions to the drug Acortine directly from the package or from the pharmacist at the pharmacy.
more... close

None known.

Undesirable effects

The information provided in Undesirable effects of Acortine is based on data of another medicine with exactly the same composition as the Acortine of the medicine (Hydrocortisone). Be careful and be sure to specify the information on the section Undesirable effects in the instructions to the drug Acortine directly from the package or from the pharmacist at the pharmacy.
more... close

Tabulated list of adverse reactions

System Organ Class

Rare

>/10,000,<1/1000

Very rare

</10,000

Not known

Immune system disorders

Hypersensitivity

Endocrine disorders

Adrenal suppression

Skin and subcutaneous tissue disorders

Skin atrophy, often irreversible, with thinning of the epidermis

Telangiectasia

Skin striae

Pustular acne

Perioral dermatitis

Rebound effect

Skin depigmentation

Dermatitis and eczema, including contact dermatitis

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.

Overdose

The information provided in Overdose of Acortine is based on data of another medicine with exactly the same composition as the Acortine of the medicine (Hydrocortisone). Be careful and be sure to specify the information on the section Overdose in the instructions to the drug Acortine directly from the package or from the pharmacist at the pharmacy.
more... close

Excessive use under occlusive dressings may produce adrenal suppression. No special procedures or antidote. Treat any adverse effects symptomatically.

Pharmacodynamic properties

The information provided in Pharmacodynamic properties of Acortine is based on data of another medicine with exactly the same composition as the Acortine of the medicine (Hydrocortisone). Be careful and be sure to specify the information on the section Pharmacodynamic properties in the instructions to the drug Acortine directly from the package or from the pharmacist at the pharmacy.
more... close

Pharmacotherapeutic group: Corticosteroid, ATC code: D07AB02.

Hydrocortisone butyrate is a potent topical corticosteroid.

Pharmacokinetic properties

The information provided in Pharmacokinetic properties of Acortine is based on data of another medicine with exactly the same composition as the Acortine of the medicine (Hydrocortisone). Be careful and be sure to specify the information on the section Pharmacokinetic properties in the instructions to the drug Acortine directly from the package or from the pharmacist at the pharmacy.
more... close

The topical activity has been demonstrated in vivo using the McKenzie-Stoughton test.

Pharmacotherapeutic group

The information provided in Pharmacotherapeutic group of Acortine is based on data of another medicine with exactly the same composition as the Acortine of the medicine (Hydrocortisone). Be careful and be sure to specify the information on the section Pharmacotherapeutic group in the instructions to the drug Acortine directly from the package or from the pharmacist at the pharmacy.
more... close
Corticosteroid, ATC code: D07AB02.

Preclinical safety data

The information provided in Preclinical safety data of Acortine is based on data of another medicine with exactly the same composition as the Acortine of the medicine (Hydrocortisone). Be careful and be sure to specify the information on the section Preclinical safety data in the instructions to the drug Acortine directly from the package or from the pharmacist at the pharmacy.
more... close

Topical administration of corticosteroids to pregnant animals can cause abnormalities of foetal development including cleft palate and intra-uterine growth retardation. There may therefore be a very small risk of such effects in the human foetus.

Theoretically, there is the possibility that if maternal systemic absorption occurred the infant's adrenal function could be affected.

Incompatibilities

The information provided in Incompatibilities of Acortine is based on data of another medicine with exactly the same composition as the Acortine of the medicine (Hydrocortisone). Be careful and be sure to specify the information on the section Incompatibilities in the instructions to the drug Acortine directly from the package or from the pharmacist at the pharmacy.
more... close

None stated.

Special precautions for disposal and other handling

The information provided in Special precautions for disposal and other handling of Acortine is based on data of another medicine with exactly the same composition as the Acortine of the medicine (Hydrocortisone). Be careful and be sure to specify the information on the section Special precautions for disposal and other handling in the instructions to the drug Acortine directly from the package or from the pharmacist at the pharmacy.
more... close

No special requirements.

Site feedback

How easy to use our site?

Commentary is required, without it we won't know how to become better
The maximum length of review is 1000 symbols

Thanks!

You help us to become better